# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5124927 | Functional | Antiviral activity against HCMV AD-169 infected in HFF cells assessed as reduction in viral replication measured after 14 days | Human betaherpesvirus 5 | 7 | ALA5120909 | organism-based format | Scientific Literature | |
2. | ALA5124928 | Toxicity | Cytotoxicity against human HFF cells infected with HCMV AD-169 virus assessed as reduction in cell viability by cell titer-glo assay | Homo sapiens | 7 | ALA5120909 | cell-based format | Scientific Literature | |
3. | ALA5124929 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human HFF cells infected with HCMV AD-169 virus assessed as reduction in cell viability by cell titer-glo assay to EC50 for antiviral activity against HCMV AD-169 infected in HFF cells assessed as inhibition of virus-induced cytopathic effect measured after 14 days | 7 | ALA5120909 | cell-based format | Scientific Literature | ||
4. | ALA5124930 | Functional | Antiviral activity against VZV Ellen infected in HFF cells assessed as reduction in viral replication measured after 14 days | Human alphaherpesvirus 3 | 7 | ALA5120909 | organism-based format | Scientific Literature | |
5. | ALA5124931 | Toxicity | Cytotoxicity against human HFF cells infected with VZV Ellen virus assessed as reduction in cell viability by cell titer-glo assay | Homo sapiens | 7 | ALA5120909 | cell-based format | Scientific Literature | |
6. | ALA5124932 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human HFF cells infected with VZV Ellen virus assessed as reduction in cell viability by cell titer-glo assay to EC50 for antiviral activity against VZV Ellen infected in HFF cells assessed as inhibition of virus-induced cytopathic effect measured after 14 days | 7 | ALA5120909 | cell-based format | Scientific Literature | ||
7. | ALA5124933 | Functional | Anti-HIV activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 11 | ALA5120909 | organism-based format | Scientific Literature | |
8. | ALA5124934 | Functional | Anti-HIV activity against wild type HIV-2 ROD infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | Human immunodeficiency virus 2 | 11 | ALA5120909 | organism-based format | Scientific Literature | |
9. | ALA5124935 | Toxicity | Cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 11 | ALA5120909 | cell-based format | Scientific Literature | |
10. | ALA5124936 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for anti-HIV activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | 11 | ALA5120909 | cell-based format | Scientific Literature | ||
11. | ALA5124937 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for anti-HIV activity against wild type HIV-2 ROD infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay | 11 | ALA5120909 | cell-based format | Scientific Literature | ||
12. | ALA5124938 | Functional | Antiviral activity against wild type HBV infected in human HepG2 2.2.15 cells assessed as reduction in viral replication pre incubated for 3 days followed by replacement with fresh compounds for another 3 days prior to pronase treatment by RT-qPCR analysis | Hepatitis B virus | 16 | ALA5120909 | organism-based format | Scientific Literature | |
13. | ALA5124940 | Functional | Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability by neutral red uptake assay | Homo sapiens | 6 | ALA5120909 | cell-based format | Scientific Literature | |
14. | ALA5124941 | Functional | Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability | Homo sapiens | 7 | ALA5120909 | cell-based format | Scientific Literature | |
15. | ALA5124942 | Functional | Antiviral activity against wild type HBV infected in human HepG2 2.2.15 cells assessed as reduction in viral replication by DNA HYB (Vision)/neutral red (Tox) assay | Hepatitis B virus | 2 | ALA5120909 | organism-based format | Scientific Literature | |
16. | ALA5124943 | Functional | Antiviral activity against wild type HBV infected in human HepG2 2.2.15 cells assessed as reduction in viral replication by DNA HYB (RI)/neutral red (Tox) assay | Hepatitis B virus | 2 | ALA5120909 | organism-based format | Scientific Literature | |
17. | ALA5124944 | Toxicity | Selectivity index, ratio of CC50 cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability to EC50 for antiviral activity against wild type HBV infected in human HepG2 2.2.15 cells assessed as reduction in viral replication by DNA HYB (Vision)/neutral red (Tox) assay | 2 | ALA5120909 | cell-based format | Scientific Literature | ||
18. | ALA5124945 | Toxicity | Selectivity index, ratio of CC50 cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability to EC50 for antiviral activity against wild type HBV infected in human HepG2 2.2.15 cells assessed as reduction in viral replication by DNA HYB (RI)/neutral red (Tox) assay | 2 | ALA5120909 | cell-based format | Scientific Literature |