# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5132331 | F | Neuroprotective activity against NMDA-induced neurotoxicity in Sprague-Dawley rat hippocampal neurons assessed as increase in cell viability at 0.1 uM incubated for 18 hrs followed by NMDA addition and measured after 0.5 hrs by MTT assay | Rattus norvegicus | 31 | ALA5131388 | cell-based format | Scientific Literature | |
2. | ALA5132332 | F | Neuroprotective activity against NMDA-induced neurotoxicity in Sprague-Dawley rat hippocampal neurons assessed as increase in cell viability at 1 uM incubated for 18 hrs followed by NMDA addition and measured after 0.5 hrs by MTT assay | Rattus norvegicus | 31 | ALA5131388 | cell-based format | Scientific Literature | |
3. | ALA5132333 | F | Neuroprotective activity against NMDA-induced neurotoxicity in Sprague-Dawley rat hippocampal neurons assessed as increase in cell viability at 10 uM incubated for 18 hrs followed by NMDA addition and measured after 0.5 hrs by MTT assay | Rattus norvegicus | 31 | ALA5131388 | cell-based format | Scientific Literature | |
4. | ALA5132334 | B | Displacement of [3H] ifenprodil from Wistar rat glutamate NMDA receptor incubated for 2 hrs by scintillation counting method | Rattus norvegicus | 5 | ALA5131388 | protein complex format | Scientific Literature | |
5. | ALA5132335 | F | Neuroprotective activity in Sprague-Dawley rat model of middle cerebral artery occlusion-induced ischemia-reperfusion injury assessed as decrease in neurological score at 20 mg/kg, po measured 24 hrs post injury by TTC staining based histological analysis | Rattus norvegicus | 4 | ALA5131388 | organism-based format | Scientific Literature | |
6. | ALA5132340 | F | Neuroprotective activity in Sprague-Dawley rat model of middle cerebral artery occlusion-induced ischemia-reperfusion injury assessed as decrease in cerebral infarction rate at 20 mg/kg, po measured 24 hrs post injury by TTC staining based histological analysis | Rattus norvegicus | 4 | ALA5131388 | organism-based format | Scientific Literature |