# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5142716 | Functional | Anti-filarial activity against Onchocerca gutturosa adult worms assessed as reduction in worm motility measured every 24 hrs for 5 days by olympus inverted microscopic analysis | Onchocerca gutturosa | 60 | ALA5137098 | organism-based format | Scientific Literature | |
2. | ALA5142717 | Physicochemical | Kinetic solubility of compound incubated for 24 hrs | 59 | ALA5137098 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5142718 | ADME | Metabolic stability in rat liver S9 fraction assessed as compound remaining at 3 uM measured at 60 mins by LC-MS/MS analysis | Rattus norvegicus | 35 | ALA5137098 | subcellular format | Scientific Literature | |
4. | ALA5142720 | ADME | Metabolic stability in human liver S9 fraction assessed as compound remaining at 3 uM measured at 60 mins by LC-MS/MS analysis | Homo sapiens | 35 | ALA5137098 | subcellular format | Scientific Literature | |
5. | ALA5142724 | Physicochemical | Octanol/water distribution coefficient, logD of the compound at pH 7.4 sonicated for 30 mins followed by 24 hrs shaking | 53 | ALA5137098 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA5142771 | Toxicity | Cytotoxicity in human TK6 cells in presence of Aroclor 1254-induced rat liver S9 fraction by micronucleus test | Homo sapiens | 1 | ALA5137098 | cell-based format | Scientific Literature |