# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5129898 | Binding | PROTAC activity at VHL/BRD4 in human MCF7 cells assessed as BRD4 degradation measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5126605 | cell-based format | Scientific Literature | |
2. | ALA5129899 | Binding | PROTAC activity at VHL/BRD4 in human MCF7 cells assessed as BRD4 degradation by measuring maximum efficacy at 50 nM measured after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5126605 | cell-based format | Scientific Literature | |
3. | ALA5129900 | Functional | Antitumor activity activity human MCF7 cells xenografted in nude mouse assessed as tumor growth inhibition at 10 mg/kg, iv administered every other day for 21 days | Homo sapiens | 1 | ALA5126605 | organism-based format | Scientific Literature |