| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5109749 | B | Binding affinity to recombinant KK-LC-1 (unknown origin) using FITC-labeled compound at 0.1 to 1000 uM incubated for 2 hrs and measured by FLISA assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA5109750 | B | Binding affinity to KK-LC-1 in KK-LC-1-positive human NUGC-4 cells using FITC-labeled compound at 1 to 1000 uM incubated for 30 mins and measured by flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5109751 | B | Binding affinity to KK-LC-1 in KK-LC-1-positive human MKN-45 cells using FITC-labeled compound at 1 to 1000 uM incubated for 30 mins and measured by flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5109752 | B | Binding affinity to KK-LC-1 in KK-LC-1-negative human HGC-27 cells using FITC-labeled compound at 1 to 1000 uM incubated for 30 mins and measured by flow cytometry assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5109753 | A | Drug uptake in KK-LC-1-positive human NUGC-4 cells using FITC-labeled compound at 100 uM incubated for 10 to 70 mins and assessed as drug internalization measured by DAPI staining method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5109754 | A | Drug uptake in KK-LC-1-negative human HGC-27 cells using FITC-labeled compound at 100 uM incubated for 10 to 70 mins and assessed as drug internalization measured by DAPI staining method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5109755 | F | Cytotoxicity against KK-LC-1-positive human NUGC-4 cells incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA5109756 | F | Cytotoxicity against KK-LC-1-positive human MKN-45 cells incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA5109757 | F | Cytotoxicity against KK-LC-1-negative human HGC-27 cells incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5109758 | U | Ratio IC50 for cytotoxicity against KK-LC-1-negative human HGC-27 cells to IC50 for cytotoxicity against KK-LC-1-positive human NUGC-4 cells | 1 | cell-based format | Scientific Literature | |||
| 11. | ALA5109759 | U | Ratio IC50 for cytotoxicity against KK-LC-1-negative human HGC-27 cells to IC50 for cytotoxicity against KK-LC-1-positive human MKN-45 cells | 1 | cell-based format | Scientific Literature | |||
| 12. | ALA5109760 | F | Cell cycle arrest in KK-LC-1-positive human NUGC-4 cells assessed as accumulation at G2/M phase at 20 nM measured after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 21.5 +/- 0.7 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5109761 | F | Cell cycle arrest in KK-LC-1-positive human NUGC-4 cells assessed as accumulation at G2/M phase at 40 nM measured after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 21.5 +/- 0.7 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5109762 | F | Cell cycle arrest in KK-LC-1-positive human NUGC-4 cells assessed as accumulation at G2/M phase at 100 nM measured after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 21.5 +/- 0.7 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5109763 | F | Cell cycle arrest in KK-LC-1-positive human MKN-45 cells assessed as increase accumulation at G2/M phase at 20 to 100 nM measured after 24 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5109764 | F | Cell cycle arrest in KK-LC-1-negative human HGC-27 cells assessed as increase accumulation at G2/M phase at 20 to 100 nM measured after 24 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5109765 | F | Cell cycle arrest in KK-LC-1-positive human NUGC-4 cells assessed as increase accumulation at G2/M phase at 100 nM measured after 0 to 48 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5109766 | F | Cell cycle arrest in KK-LC-1-positive human MKN-45 cells assessed as increase accumulation at G2/M phase at 100 nM measured after 0 to 48 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5109767 | F | Cell cycle arrest in KK-LC-1-negative human HGC-27 cells assessed as increase accumulation at G2/M phase at 100 nM measured after 0 to 48 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5109768 | F | Inhibition of colony formation in KK-LC-1-positive human NUGC-4 cells assessed as decrease in colonies incubated for 24 hrs followed by exposure to 2 Gy gamma irradiation by crystal violet staining based clonogenic assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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