| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5164333 | F | Agonist activity at human MC1R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA5164336 | F | Agonist activity at human MC5R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA5164340 | F | Antagonist activity at human MC1R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 10 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA5164341 | F | Antagonist activity at human MC3R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 30 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA5164343 | F | Agonist activity at human MC3R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA5164344 | F | Agonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA5164346 | F | Antagonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 70 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA5164347 | F | Antagonist activity at human MC5R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 500 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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