| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5144823 | F | Antiviral activity against HIV1 with RT F227L + V106A mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 2. | ALA5144824 | F | Antiviral activity against HIV1 3B infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 3. | ALA5144825 | T | Toxicity in mock-infected human MT4 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 4. | ALA5144826 | T | Selectivity index, ratio of CC50 for toxicity in mock-infected human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for antiviral activity against HIV1 3B infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | 18 | cell-based format | Scientific Literature | |||
| 5. | ALA5144827 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT L100I mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 6. | ALA5144828 | F | Antiviral activity against HIV1 with RT L100I mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 7. | ALA5144829 | F | Antiviral activity against HIV1 with RT K103N mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 8. | ALA5144830 | F | Antiviral activity against HIV1 with RT Y181C mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 9. | ALA5144831 | F | Antiviral activity against HIV1 with RT Y188L mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 10. | ALA5144832 | F | Antiviral activity against HIV1 with RT E138K mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 11. | ALA5144833 | F | Antiviral activity against HIV1 with RT RES056 mutant infected in human MT4 cells cells assessed as protection against viral-induced cytopathogenecity by MTT assay | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 12. | ALA5144834 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT K103N mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 13. | ALA5144835 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT Y181C mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 14. | ALA5144836 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT Y188L mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 15. | ALA5144837 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT E138K mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 16. | ALA5144838 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT F227L + V106A mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 17. | ALA5144839 | F | Resistance index, ratio of EC50 for antiviral activity against HIV1 with RT RES056 mutant infected in human MT4 cells to EC50 for antiviral activity against wild type HIV1 infected in human MT4 cells | Human immunodeficiency virus 1 | 18 | organism-based format | Scientific Literature | ||
| 18. | ALA5144840 | B | Inhibition of HIV1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporation | Human immunodeficiency virus 1 | 4 | single protein format | Scientific Literature | ||
| 19. | ALA5144841 | P | Solubility in water at pH 7.4 | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 20. | ALA5144842 | P | Solubility in water at pH 7 | 4 | small-molecule physicochemical format | Scientific Literature |
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