Drug uptake in mouse 4T1 cells assessed as increase in fluorescence signal pretreated with cTMPT1 peptide for 30 mins followed by compound addition by flow cytometry analysis
Drug accumulation in BALB/c mouse liver assessed as increase in fluorescence intensity at 30 uM, iv measured after 30 mins by NIR fluorescence imaging analysis
Drug accumulation in BALB/c mouse kidney assessed as increase in fluorescence intensity at 30 uM, iv measured after 2 hrs by NIR fluorescence imaging analysis
Drug uptake in tumor of mouse 4T1 cells allografted in BALB/c mouse assessed as increase in fluorescence signal at 30 uM, iv measured after 12 to 48 hrs by IVIS spectrum in vivo imaging analysis
Drug uptake in tumor of mouse 4T1 cells allografted in BALB/c mouse assessed as increase in fluorescence signal at 30 uM, iv measured up to 48 hrs pretreated with cTMTP1 peptide followed by compound addition by IVIS spectrum in vivo imaging analysis
Drug uptake in tumor of mouse 4T1 cells allografted in BALB/c mouse assessed as increase in ratio of fluorescence signal in tumor to normal tissue at 30 uM, iv measured after 12 to 48 hrs by NIR fluorescence imaging analysis
Drug uptake in tumor of mouse 4T1 cells allografted in BALB/c mouse assessed as increase in fluorescence signal at 30 uM, iv measured after 12 hrs by NIR fluorescence imaging analysis
Drug uptake in lymph node of mouse 4T1 cells allografted in BALB/c mouse assessed as increase in fluorescence signal at 30 uM, iv measured after 24 to 48 hrs by NIR fluorescence imaging analysis
Drug uptake in lymph node of mouse 4T1 cells allografted in BALB/c mouse assessed as increase in fluorescence signal at 30 uM, iv measured up to 48 hrs pretreated for cTMTP1 peptide followed by compound addition by NIR fluorescence imaging analysis