| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5107689 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MOLM-14 cells assessed as decrease in FLT3 protein expression at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA5107690 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as decrease in FLT3 protein expression at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA5107692 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as decrease in AXL protein expression at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA5107694 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as inhibition of FLT3 phosphorylation at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5107695 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as inhibition of STAT5 phosphorylation at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!