| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5126113 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of CDK12 degradation incubated for 15 hrs by immunoblotting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA5126116 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of CDK12 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 3. | ALA5126117 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of CDK13 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 4. | ALA5126118 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of CDK13 degradation incubated for 15 hrs by immunoblotting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA5126119 | B | Protac activity at CRBN/CDK12 in human MFM-223 cells assessed as induction of degradation by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5126120 | B | Protac activity at CRBN/CDK13 in human MFM-223 cells assessed as induction of degradation by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5126121 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of degradation by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5126122 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of degradation by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5126123 | B | Protac activity at CRBN/CDK12 in human MFM-223 cells assessed as induction of degradation at 500 nM incubated upto 24 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5126124 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of degradation at 500 nM incubated upto 24 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5126125 | B | Protac activity at CRBN/CDK13 in human MFM-223 cells assessed as induction of degradation at 500 nM measured after 4 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5126126 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of degradation at 500 nM measured after 4 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5126127 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as degradation of CDK12 at 500 nM measured after 6 hrs in presence of carfilzomib by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5126128 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as degradation of CDK13 at 500 nM measured after 6 hrs in presence of carfilzomib by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5126129 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as degradation of CDK12 at 500 nM measured after 6 hrs in presence of bafilomycin by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5126130 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as degradation of CDK13 at 500 nM measured after 6 hrs in presence of bafilomycin by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5126131 | B | Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as inhibition of degradation of CDK12 at 500 nM measured after 6 hrs in presence of thalidomide | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5126132 | B | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as inhibition of degradation of CDK13 at 500 nM measured after 6 hrs presence of thalidomide | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5126133 | F | Downregulation of CDK12 in human MDA-MB-231 cells at 100 to 500 nM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5126134 | F | Downregulation of CDK13 in human MDA-MB-231 cells at 100 to 500 nM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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