| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5130985 | B | Inhibition of TEV cleavage site-fused His6-tagged WNK1 (194 to 483 residues) (unknown origin) expressed in Rosetta (DE3) cells using GST-OSR1(314 to 344) peptide as substrate incubated for 2 hrs by kinase-glo luminescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA5130986 | B | Inhibition of TEV cleavage site-fused His6-tagged WNK1 (194 to 483 residues) (unknown origin) expressed in Rosetta (DE3) cells using GST-OSR1(314 to 344) peptide as substrate measured after 30 mins by [gamma-32P]-ATP based liquid scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA5130987 | B | Inhibition of WNK1 in human MDA-MB-231 cells assessed as reduction in OSR1 phosphorylation measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5130988 | T | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability up to 12 uM measured after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5130989 | B | Inhibition of WNK1 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA5130990 | B | Inhibition of WNK3 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA5130994 | B | Selectivity ratio of IC50 for WNK3 (118 to 409 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 to IC50 for TEV cleavage site-fused His6-tagged WNK1 (194 to 483 residues) (unknown origin) expressed in Rosetta (DE3) cells | Homo sapiens | 1 | cell-based format | Scientific Literature |
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