# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5157441 | Toxicity | Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation with 6-CFL and measured after 15 mins by fluorescence based analysis | Homo sapiens | 4 | ALA5154691 | cell-based format | Scientific Literature | |
2. | ALA5157443 | Binding | Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 mins followed by substrate addition and measured after 15 mins by liquid scintillation counting analysis | Homo sapiens | 37 | ALA5154691 | cell-based format | Scientific Literature | |
3. | ALA5157444 | Binding | Inhibition of GLUT9 (unknown origin) expressed in HEK293T cells assessed as inhibition of uric acid-induced current at 10 uM by whole cell patch clamp technique | Homo sapiens | 4 | ALA5154691 | cell-based format | Scientific Literature | |
4. | ALA5157449 | Toxicity | Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincubated for 15 mins followed by incubation with ATP and substrate for 5 mins by liquid scintillation counting analysis | Homo sapiens | 4 | ALA5154691 | cell membrane format | Scientific Literature |