#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5163214	Binding	Inhibition of alpha2c adrenergic receptor (unknown origin)	Homo sapiens	4	ALA5154826	single protein format	Scientific Literature
2.	ALA5163215	ADME	Free plasma concentration in Athymic BALB/c nude mouse xenografted with human Karpas-422 cells at 20 mg/kg, po after 12 hrs by HPLC-MS/MS analysis	Mus musculus	1	ALA5154826	organism-based format	Scientific Literature
3.	ALA5163217	ADME	Intrinsic clearance in human hepatocytes measured per 10^6 cells	Homo sapiens	2	ALA5154826	cell-based format	Scientific Literature
4.	ALA5163232	Binding	Inhibition of PRC2 (unknown origin) assessed as reduction in H3K27 trimethylation using H3K27Me0 peptide (21 to 44 residues) as substrate by measuring SAH formation by LC-MS analysis	Homo sapiens	15	ALA5154826	assay format	Scientific Literature
5.	ALA5163233	ADME	Clearance in wild type Beagle dog at 2 mg/kg, po or 1 mg/kg, iv after 1 week by LC-MS/MS analysis	Canis lupus familiaris	2	ALA5154826	organism-based format	Scientific Literature
6.	ALA5163235	Binding	Inhibition of PRC2 in human G-401 cells assessed as H3K27 methylation status incubated for 48 hrs by ELISA method	Homo sapiens	8	ALA5154826	cell-based format	Scientific Literature
7.	ALA5163236	Functional	Antiproliferative activity against human KARPAS-422 cells expressing EZH2 mutant assessed as inhibition of cell growth after 14 days by beckman coulter counting method	Homo sapiens	5	ALA5154826	cell-based format	Scientific Literature
8.	ALA5163237	Physicochemical	Lipophilicity, logD of the compound at pH 7.4 by LC with tandem MS analysis		5	ALA5154826	small-molecule physicochemical format	Scientific Literature
9.	ALA5163238	Physicochemical	Dissociation constant, pKa of compound		4	ALA5154826	small-molecule physicochemical format	Scientific Literature
10.	ALA5163240	ADME	Permeability across apical to basolateral side in human Caco-2 cells at 10 uM incubated for 2 hrs by LC/MS/MS analysis	Homo sapiens	4	ALA5154826	cell-based format	Scientific Literature
11.	ALA5163244	ADME	Oral bioavailability in Sprague-Dawley rat at 2 mg/kg	Rattus norvegicus	4	ALA5154826	organism-based format	Scientific Literature
12.	ALA5163245	ADME	Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	5	ALA5154826	microsome format	Scientific Literature
13.	ALA5163246	ADME	Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	5	ALA5154826	microsome format	Scientific Literature
14.	ALA5163247	ADME	Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	11	ALA5154826	microsome format	Scientific Literature
15.	ALA5163249	Functional	Antagonist activity against alpha2a adrenergic receptor (unknown origin)	Homo sapiens	2	ALA5154826	assay format	Scientific Literature
16.	ALA5163250	Physicochemical	High throughput solubility of the compound at pH 1 after 16 to 24 hrs by MS/MS analysis		2	ALA5154826	small-molecule physicochemical format	Scientific Literature
17.	ALA5163251	Physicochemical	High throughput solubility of the compound at pH 7 after 16 to 24 hrs by MS/MS analysis		3	ALA5154826	small-molecule physicochemical format	Scientific Literature
18.	ALA5163252	Physicochemical	High throughput solubility of the compound in SGF after 16 to 24 hrs by MS/MS analysis		2	ALA5154826	small-molecule physicochemical format	Scientific Literature
19.	ALA5163253	Physicochemical	High throughput solubility of the compound in FaSSIF after 16 to 24 hrs by MS/MS analysis		2	ALA5154826	small-molecule physicochemical format	Scientific Literature
20.	ALA5163254	Physicochemical	High throughput solubility of the compound in FeSSIF after 16 to 24 hrs by MS/MS analysis		2	ALA5154826	small-molecule physicochemical format	Scientific Literature