#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5151004	B	Inhibition of human Notum using OPTS substrate incubated for 1 hr by fluorescence based assay	Homo sapiens	7	ALA5149981	single protein format	Scientific Literature
2.	ALA5151011	A	Protein binding in mouse plasma assessed as unbound fraction	Mus musculus	1	ALA5149981	cell-free format	Scientific Literature
3.	ALA5151013	A	Brain to plasma ratio in mouse at 30 mg/kg, po bid for 30 days by LC-MS analysis	Mus musculus	1	ALA5149981	organism-based format	Scientific Literature
4.	ALA5151015	A	Half life in mouse at 1 mg/kg,iv for 30 days by LC-MS analysis	Mus musculus	1	ALA5149981	organism-based format	Scientific Literature
5.	ALA5151016	A	Oral bioavailability in mouse at 30 mg/kg, bid for 30 days by LC-MS analysis	Mus musculus	1	ALA5149981	organism-based format	Scientific Literature
6.	ALA5151017	A	Cmax in mouse at 10 mg/kg, po bid for 30 days by LC-MS analysis	Mus musculus	1	ALA5149981	organism-based format	Scientific Literature
7.	ALA5151018	A	AUC (0-infinity) in mouse at 10 mg/kg, po bid for 30 days by LC-MS analysis	Mus musculus	1	ALA5149981	organism-based format	Scientific Literature
8.	ALA5166899	A	Apparent permeability of the compound across basolateral side to apical side in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis	Homo sapiens	1	ALA5154906	cell-based format	Scientific Literature
9.	ALA5166900	A	Apparent permeability of the compound across apical to basolateral side in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis	Homo sapiens	1	ALA5154906	cell-based format	Scientific Literature
10.	ALA5166901	B	Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluorescence based assay	Homo sapiens	42	ALA5154906	cell-based format	Scientific Literature
11.	ALA5166902	P	Octanol/buffer distribution coefficient, logD of compound at pH 7.4 by shake flask method based LC-UV analysis		2	ALA5154906	small-molecule physicochemical format	Scientific Literature
12.	ALA5166903	P	Aqueous solubility of compound in PBS at pH 7.4		7	ALA5154906	small-molecule physicochemical format	Scientific Literature
13.	ALA5166904	A	Metabolic stability in mouse liver microsomes assessed as intrinsic clearance	Mus musculus	7	ALA5154906	microsome format	Scientific Literature
14.	ALA5166905	A	Metabolic stability in human liver microsomes assessed as intrinsic clearance	Homo sapiens	7	ALA5154906	microsome format	Scientific Literature
15.	ALA5166906	A	Apparent permeability across apical to basolateral side in MDCK-MDR1 cells	Canis lupus familiaris	7	ALA5154906	cell-based format	Scientific Literature
16.	ALA5166907	A	Apparent permeability across basolateral to apical side in MDCK-MDR1 cells	Canis lupus familiaris	7	ALA5154906	cell-based format	Scientific Literature
17.	ALA5166908	A	Efflux ratio of apparent permeability from apical to basolateral side over basolateral to apical side in MDCK-MDR1 cells	Canis lupus familiaris	7	ALA5154906	cell-based format	Scientific Literature
18.	ALA5166909	A	Permeability coefficient in C57BL6 mouse assessed as brain to plasma ratio at 10 mg/kg, po	Mus musculus	2	ALA5154906	organism-based format	Scientific Literature
19.	ALA5166910	B	Inhibition of full length recombinant human Notum expressed in HEK293S cells expressing TCF-LEF preincubated for 30 mins followed by Wnt-3A addition and measured after 1 hr by luminescence based microplate reader analysis	Homo sapiens	1	ALA5154906	cell-based format	Scientific Literature
20.	ALA5166911	A	Clearance in C57BL6 mouse at 1 mg/kg, iv	Mus musculus	1	ALA5154906	organism-based format	Scientific Literature