# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5152971 | B | Inhibition of Escherichia coli GroEL expressed in NEB-5-alpha Escherichia coli cells/Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of GroEL/ES-mediated dMDH refolding by reporter analysis | Escherichia coli | 21 | ALA5150040 | cell-based format | Scientific Literature | |
2. | ALA5152972 | B | Inhibition of Escherichia coli GroEL expressed in NEB-5-alpha Escherichia coli cells/Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of GroEL/ES-mediated dRho refolding by reporter analysis | Escherichia coli | 21 | ALA5150040 | cell-based format | Scientific Literature | |
3. | ALA5152973 | B | Inhibition of human mitochondrial HSP60 expressed in Escherichia coli Rosetta 2 (DE3) cells/human mitochondrial HSP10 expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells assessed as inhibition of GroEL/ES-mediated dMDH refolding by reporter analysis | Homo sapiens | 21 | ALA5150040 | mitochondrion format | Scientific Literature | |
4. | ALA5152974 | B | Inhibition of refolded rhodanese reporter enzyme (unknown origin) | Homo sapiens | 21 | ALA5150040 | assay format | Scientific Literature | |
5. | ALA5152975 | B | Inhibition of refolded MDH reporter enzyme (unknown origin) | Homo sapiens | 21 | ALA5150040 | assay format | Scientific Literature | |
6. | ALA5152976 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay | Homo sapiens | 21 | ALA5150040 | cell-based format | Scientific Literature | |
7. | ALA5152977 | F | Cytotoxicity against human DLD-1 cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay | Homo sapiens | 21 | ALA5150040 | cell-based format | Scientific Literature | |
8. | ALA5152978 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay | Homo sapiens | 21 | ALA5150040 | cell-based format | Scientific Literature | |
9. | ALA5152979 | F | Cytotoxicity against p53-/- human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay | Homo sapiens | 21 | ALA5150040 | cell-based format | Scientific Literature | |
10. | ALA5152980 | T | Cytotoxicity against human FHs74Int cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay | Homo sapiens | 21 | ALA5150040 | cell-based format | Scientific Literature | |
11. | ALA5152981 | T | Cytotoxicity against human FHC cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay | Homo sapiens | 21 | ALA5150040 | cell-based format | Scientific Literature | |
12. | ALA5152982 | T | Selectivity index, ratio of CC50 for cytotoxicity against non-cancerous cells to EC50 for cytotoxicity against human HCT-116 cells | 18 | ALA5150040 | cell-based format | Scientific Literature | ||
13. | ALA5152984 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability at 0.01 to 100 uM by Trypan Blue staining based analysis | Homo sapiens | 2 | ALA5150040 | cell-based format | Scientific Literature | |
14. | ALA5152985 | F | Induction of apoptosis in human HCT-116 cells at 0.1 to 100 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry | Homo sapiens | 2 | ALA5150040 | cell-based format | Scientific Literature | |
15. | ALA5152986 | F | Induction of necrotic cell death in human HCT-116 cells at 0.1 to 100 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry | Homo sapiens | 2 | ALA5150040 | cell-based format | Scientific Literature | |
16. | ALA5152987 | F | Inhibition of clonogenicity in human HCT-116 cells at > 1 uM incubated for 72 hrs followed by incubation in fresh medium for 7 days by crystal violet staining based analysis | Homo sapiens | 2 | ALA5150040 | cell-based format | Scientific Literature | |
17. | ALA5152989 | F | Inhibition of cell migration in human HCT-116 cells measured after 26 hrs by scratch wound healing assay | Homo sapiens | 1 | ALA5150040 | cell-based format | Scientific Literature | |
18. | ALA5152992 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by AlamarBlue-based assay relative to control | Homo sapiens | 1 | ALA5150040 | cell-based format | Scientific Literature |