#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5160316	Functional	Antineuroinflammatory activity in paclitaxel induced C57BL/6J mouse model of peripheral neuropathy assessed as decrease in M1 macrophage infiltration into DRG at 5 mg/kg, ip administered prior to paclitaxel treatment and measured after 7 days by double immunofluorescence staining based assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
2.	ALA5160317	Functional	Antineuroinflammatory activity against paclitaxel induced peripheral neuropathy in C57BL/6J mouse model assessed as decrease in M2 macrophage infiltration into DRG at 10 to 20 mg/kg, ip administered prior to paclitaxel treatment and measured after 7 days by double immunofluorescence staining based assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
3.	ALA5160318	Functional	Neuroprotective activity against paclitaxel-induced neurotoxicity in mouse primary DRG neuron assessed as induction of neurite outgrowth at 1000 nM relative to control	Mus musculus	13	ALA5154771	tissue-based format	Scientific Literature
4.	ALA5160319	Functional	Neuroprotective activity against paclitaxel-induced thermhypesthesia in C57BL/6J mouse neuropathy model assessed as increase in thermal sensation by measuring tail flick latency at 10 to 20 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by tail immersion assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
5.	ALA5160320	Functional	Neuroprotective activity against paclitaxel-induced mechanical allodynia in C57BL/6J mouse neuropathy model assessed as reduction in mechanical hypersensitivity by measuring paw withdrawal threshold at 10 to 20 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by von Frey filament assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
6.	ALA5160321	Functional	Neuroprotective activity against paclitaxel-induced thermhypesthesia in C57BL/6 mouse neuropathy model assessed as increase in thermal sensation by measuring tail flick latency at 5 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by tail immersion assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
7.	ALA5160322	Functional	Neuroprotective activity against paclitaxel-induced mechanical allodynia in C57BL/6 mouse neuropathy model assessed as reduction in mechanical hypersensitivity by measuring paw withdrawal threshold at 5 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by von Frey filament assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
8.	ALA5160323	Functional	Neuroprotective activity against paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as myelinated fiber damage at 5 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by TEM imaging	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
9.	ALA5160324	Functional	Neuroprotective activity against paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as non-myelinated fiber damage at 5 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by TEM imaging	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
10.	ALA5160325	Functional	Neuroprotective activity against paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as rescue of axonal damage in small fiber by measuring G-ratio at 10 to 20 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
11.	ALA5160326	Functional	Neuroprotective activity against paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as rescue of axonal damage in large fiber by measuring G-ratio at 5 to 20 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
12.	ALA5160327	Functional	Neuroprotective activity against paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as decrease in swollen mitochondria at 5 to 20 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by TEM imaging analysis	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
13.	ALA5160328	Functional	Neuroprotective activity against paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as decrease in vacuolated mitochondria at 5 to 20 mg/kg, ip administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by TEM imaging analysis	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
14.	ALA5160329	Functional	Neuroprotective activity against ip dosed paclitaxel-induced C57BL/6J mouse sciatic nerve damage model assessed as rescue of fiber loss administered 1 hr prior to paclitaxel treatment on day 1, 3, 5, 7 and measured weekly for 5 weeks by TEM imaging	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
15.	ALA5160330	Functional	Antineuroinflammatory activity against paclitaxel induced systemic inflammation in C57BL/6J mouse model assessed as decrease in MCP-1 level at 5 to 15 mg/kg, ip measured after 14 days	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
16.	ALA5160331	Functional	Antineuroinflammatory activity against paclitaxel induced systemic inflammation in C57BL/6J mouse model assessed as decrease in RANTES level at 5 to 15 mg/kg, ip measured after 14 days	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
17.	ALA5160332	Functional	Antineuroinflammatory activity against paclitaxel induced systemic inflammation in C57BL/6J mouse model assessed as decrease in proinflammatory cytokines level at 5 to 15 mg/kg, ip measured after 14 days	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
18.	ALA5160333	Functional	Antineuroinflammatory activity against paclitaxel induced peripheral neuropathy in C57BL/6J mouse model assessed as decrease in M1 macrophage infiltration into DRG at 10 to 20 mg/kg, ip administered prior to paclitaxel treatment and measured after 7 days by double immunofluorescence staining based assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
19.	ALA5160334	Functional	Antineuroinflammatory activity in paclitaxel induced C57BL/6J mouse model of peripheral neuropathy assessed as decrease in M2 macrophage infiltration into DRG at 5 mg/kg, ip administered prior to paclitaxel treatment and measured after 7 days by double immunofluorescence staining based assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature
20.	ALA5160335	Functional	Antineuroinflammatory activity against paclitaxel induced peripheral neuropathy in C57BL/6J mouse model assessed as decrease in M1 microglia activation in DRG neurons at 5 to 20 mg/kg, ip administered prior to paclitaxel treatment and measured after 7 days by double immunofluorescence staining based assay	Mus musculus	1	ALA5154771	organism-based format	Scientific Literature