# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5127369 | B | Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Mus musculus | 60 | ALA5126517 | assay format | Scientific Literature | |
2. | ALA5127371 | B | Inhibition of GST-fused mouse recombinant CLK3 expressed in Escherichia coli at 10 uM using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Mus musculus | 13 | ALA5126517 | assay format | Scientific Literature | |
3. | ALA5127373 | B | Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Mus musculus | 60 | ALA5126517 | assay format | Scientific Literature | |
4. | ALA5127376 | B | Inhibition of GST-fused mouse recombinant CLK2 expressed in Escherichia coli at 10 uM using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Mus musculus | 6 | ALA5126517 | assay format | Scientific Literature | |
5. | ALA5127377 | B | Inhibition of GST-fused human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 61 | ALA5126517 | assay format | Scientific Literature | |
6. | ALA5127379 | B | Inhibition of GST-fused human recombinant DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 58 | ALA5126517 | assay format | Scientific Literature | |
7. | ALA5127381 | B | Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 59 | ALA5126517 | assay format | Scientific Literature | |
8. | ALA5127383 | B | Inhibition of GST-fused human recombinant DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 53 | ALA5126517 | assay format | Scientific Literature | |
9. | ALA5127385 | B | Inhibition of porcine brain GSK-3alpha/beta at 10 uM using YRRAAVPPSPSLSRHSSPHQpSEDEEE as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Sus scrofa | 14 | ALA5126517 | tissue-based format | Scientific Literature | |
10. | ALA5127386 | B | Inhibition of human recombinant Pim1 expressed in Escherichia coli using histone H1 as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 52 | ALA5126517 | assay format | Scientific Literature | |
11. | ALA5127389 | B | Inhibition of human recombinant CK2 at 10 uM using RRRDDDSDDD peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 22 | ALA5126517 | protein format | Scientific Literature | |
12. | ALA5127390 | T | Neurotoxicity against mouse HT-22 cells assessed as cell survival treated for 24 hrs by MTS assay | Mus musculus | 22 | ALA5126517 | cell-based format | Scientific Literature | |
13. | ALA5127391 | F | Neuroprotective activity against glutamate-induced cell death in mouse HT-22 cells treated for 24 hrs by MTS assay | Mus musculus | 41 | ALA5126517 | cell-based format | Scientific Literature | |
14. | ALA5127392 | B | Induction of PI3K/mTor-dependent autophagy in human U2OS cells assessed as number of LC3 foci per cell at 10 uM measured after 4 hrs | Homo sapiens | 64 | ALA5126517 | cell-based format | Scientific Literature | |
15. | ALA5127393 | B | Modulation of CLK1 pre-mRNA splicing in mouse HT-22 cells assessed as inclusion of CLK1 exon 4 by measuring change in threshold cycle at 10 uM measured after 4 hrs by real time PCR analysis | Mus musculus | 64 | ALA5126517 | cell-based format | Scientific Literature | |
16. | ALA5127394 | B | Inhibition of DYRK1A in human SH-SY5Y overexpressing Tau4R cells assessed as phosphorylated Tau Thr212 residue level at 10 uM incubated for 6 hrs by western blot analysis relative to control | Homo sapiens | 64 | ALA5126517 | cell-based format | Scientific Literature | |
17. | ALA5127395 | F | Antagonist activity at CP-55940-activated CB1 receptor (unknown origin) at 10 uM by beta-arrestin assay relative to control | Homo sapiens | 64 | ALA5126517 | assay format | Scientific Literature | |
18. | ALA5127396 | F | Antagonist activity at CP-55940-activated CB1 receptor (unknown origin) by beta-arrestin assay | Homo sapiens | 8 | ALA5126517 | assay format | Scientific Literature |