| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5141730 | B | Displacement of [3H]U69593 from human KOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting method | Homo sapiens | 18 | ALA5137076 | cell membrane format | Scientific Literature | |
| 2. | ALA5141731 | B | Displacement of [3H]DAMGO from rat MOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting method | Rattus norvegicus | 18 | ALA5137076 | cell membrane format | Scientific Literature | |
| 3. | ALA5141732 | B | Displacement of [3H]DPDPE from rat DOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting method | Rattus norvegicus | 18 | ALA5137076 | cell membrane format | Scientific Literature | |
| 4. | ALA5141733 | B | Selectivity index, ratio of Ki for displacement of [3H]DAMGO from rat MOR expressed in CHO cell membranes to Ki for displacement of [3H]U69593 from human KOR expressed in CHO cell membranes | Homo sapiens | 18 | ALA5137076 | cell-based format | Scientific Literature | |
| 5. | ALA5141734 | B | Selectivity index, ratio of Ki for displacement of [3H]DPDPE from rat DOR expressed in CHO cell membranes to Ki for displacement of [3H]U69593 from human KOR expressed in CHO cell membranes | Homo sapiens | 18 | ALA5137076 | cell-based format | Scientific Literature | |
| 6. | ALA5141735 | F | Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assay | Homo sapiens | 5 | ALA5137076 | cell membrane format | Scientific Literature | |
| 7. | ALA5141736 | F | Agonist activity at human KOR expressed in CHO cell membranes assessed as maximal activity after 1 hr by [35S]GTPgammaS binding assay relative to control | Homo sapiens | 6 | ALA5137076 | cell membrane format | Scientific Literature | |
| 8. | ALA5141737 | F | Agonist activity at rat MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assay | Rattus norvegicus | 6 | ALA5137076 | cell membrane format | Scientific Literature | |
| 9. | ALA5141738 | F | Agonist activity at rat MOR expressed in CHO cell membranes assessed as maximal activity after 1 hr by [35S]GTPgammaS binding assay relative to control | Rattus norvegicus | 6 | ALA5137076 | cell membrane format | Scientific Literature | |
| 10. | ALA5141739 | F | Agonist activity at rat DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assay | Rattus norvegicus | 5 | ALA5137076 | cell membrane format | Scientific Literature | |
| 11. | ALA5141740 | F | Agonist activity at rat DOR expressed in CHO cell membranes assessed as maximal activity after 1 hr by [35S]GTPgammaS binding assay relative to control | Rattus norvegicus | 6 | ALA5137076 | cell membrane format | Scientific Literature | |
| 12. | ALA5141741 | F | Antinociceptive activity in ip dosed Kunming mouse assessed as reduction in nociceptive response after 4 hrs by hot plate test | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 13. | ALA5141742 | F | Antinociceptive activity in ip dosed Kunming mouse assessed as reduction in nociceptive response after 4 hrs by abdominal constriction test | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 14. | ALA5141743 | F | Antinociceptive activity in Kunming mouse assessed as reduction in nociceptive response at 2 mg/kg, ip after 24 hrs by hot plate test | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 15. | ALA5141744 | F | Antinociceptive activity in Kunming mouse assessed as reduction in nociceptive response at 2 mg/kg, ip after 4 hrs pretreated with KOR antagonist Nor-BNI by abdominal constriction test | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 16. | ALA5141745 | F | Antinociceptive activity in Kunming mouse assessed as reduction in nociceptive response at 2 mg/kg, ip after 4 hrs pretreated with MOR antagonist beta-FNA by abdominal constriction test | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 17. | ALA5141746 | T | Toxicity in CD-1 mouse assessed as conditional preference aversion at ED50, ip administered for 7 day | Mus musculus | 2 | ALA5137076 | organism-based format | Scientific Literature | |
| 18. | ALA5141747 | T | Toxicity in CD-1 mouse assessed as conditional preference aversion at ED90, ip administered for 7 day | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 19. | ALA5141748 | T | Toxicity in Kunming mouse assessed as effect on spontaneous locomotor activity at ED50 to ED90, ip after 4 hrs followed by locomotion measured for 1 hr | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature | |
| 20. | ALA5141749 | T | Toxicity in ICR mouse assessed as reduction in time stayed in rod at ED50 to ED90, ip for 4 hrs by rotarod test | Mus musculus | 1 | ALA5137076 | organism-based format | Scientific Literature |
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