| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5106974 | B | Inhibition of Clostridium histolyticum collagenase unit of ColG at 100 uM relative to control | Hathewaya histolytica | 6 | single protein format | Scientific Literature | ||
| 2. | ALA5106983 | B | Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seconds by FRET based assay | Bacillus cereus | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA5106987 | B | Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColA at 100 uM relative to control | Bacillus cereus | 6 | single protein format | Scientific Literature | ||
| 4. | ALA5106988 | B | Inhibition of Clostridium histolyticum peptidase unit of CoLH at 100 uM relative to contol | Hathewaya histolytica | 6 | single protein format | Scientific Literature | ||
| 5. | ALA5106989 | B | Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA5106990 | B | Inhibition of human recombinant MMP-2 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 7. | ALA5106991 | B | Inhibition of human recombinant MMP-3 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 8. | ALA5106992 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA5106993 | T | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5106994 | T | Cytotoxicity against human NHDF cells assessed as reduction in cell viability | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA5106995 | T | Cytotoxicity against dog MDCK-II cells assessed as reduction in cell viability | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA5106998 | B | Inhibition of full length Bacillus cereus ColQ1 assessed as reduction in Col 1 cleavage at 1.5 to 12.5 uM incubated for 3 hrs by SDS-PAGE analysis | Bacillus cereus | 9 | single protein format | Scientific Literature | ||
| 13. | ALA5107002 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as suppression of gelatin lysis incubated for 1 to 6 hrs by coomassie brilliant blue staining based zymography analysis | Bacillus cereus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5107007 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as protection of spindle shape morphology at > 100 uM incubated for 1 to 6 hrs by coomassie brilliant blue staining based SDS-PAGE analysis | Bacillus cereus | 10 | cell-based format | Scientific Literature | ||
| 15. | ALA5107008 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as fibrillar extra cellular matrix at > 100 uM incubated for 1 to 6 hrs by coomassie brilliant blue staining based SDS-PAGE analysis | Bacillus cereus | 10 | cell-based format | Scientific Literature | ||
| 16. | ALA5107009 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as reduction in LDH release at > 100 uM incubated for 30 mins by LDH assay | Bacillus cereus | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA5107017 | B | Reversible inhibition of Clostridium histolyticum peptidase domain of ColH at 1.25 uM using quenched fluorescent FSI-1 as substrate incubated for 2 min by rapid dilution assay | Hathewaya histolytica | 4 | single protein format | Scientific Literature | ||
| 18. | ALA5107018 | B | Reversible inhibition of Clostridium histolyticum collagenase unit of ColG at 7.5 uM using quenched fluorescent FSI-1 as substrate incubated for 2 min by rapid dilution assay | Hathewaya histolytica | 4 | single protein format | Scientific Literature | ||
| 19. | ALA5107019 | B | Irreversible inhibition of Bacillus cereus collagenase unit ColQ1 assessed as residual activity at 0.125 uM using quenched fluorescent FSI-1 as substrate incubated for 2 min by rapid dilution assay | Bacillus cereus | 2 | single protein format | Scientific Literature | ||
| 20. | ALA5107020 | B | Irreversible inhibition of Bacillus cereus collagenase unit ColA at 0.125 uM using quenched fluorescent FSI-1 as substrate incubated for 2 min by rapid dilution assay | Bacillus cereus | 2 | single protein format | Scientific Literature |
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