| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5140227 | T | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 50 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA5140228 | T | Cytotoxicity against human 1321N1 cells assessed as reduction in cell viability at 50 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA5140229 | T | Cytotoxicity against HEK293 cells assessed as reduction in cell viability at 50 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA5140231 | B | Antagonist activity against human P2X2R stably transfected in human 1321N1 cells at 50 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA5140232 | B | Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 6. | ALA5140235 | B | Antagonist activity against human P2X5R stably transfected in human 1321N1 cells at 50 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA5140236 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 8. | ALA5140244 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as BzATP EC50 at 0.05 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5140245 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as BzATP EC50 at 0.1 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5140246 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as BzATP EC50 at 0.2 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5140253 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as BzATP Emax at 0.05 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5140254 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as BzATP Emax at 0.1 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5140255 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as BzATP Emax at 0.2 uM incubated for 30 mins by Fura-2 AM staining based calcium influx assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5140256 | B | Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as reduction in BzATP-induced activity incubated for 5 to 10 mins by EtBr staining based fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature |
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