# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5125545 | B | Inhibition of SETD2 (1434 to 1711 residues) (unknown origin) using SAM and biotin-Ahx-RKSAPATGGVKKPHR-NH2 as substrate preincubated for 30 mins followed by substrate addition by topcount scintillation counting method | Homo sapiens | 10 | single protein format | Scientific Literature | ||
2. | ALA5125546 | B | Inhibition of SETD2 in human A549 cells assessed as reduction in H3K36me3 incubated for 3 days by in-cell western assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
3. | ALA5125547 | F | Antiproliferative activity against human KMS-34 cells assessed as reduction in cell viability incubated for 14 days by CellTiter-glo luminescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
4. | ALA5125548 | A | Apparent permeability across apical to basal side in human Caco-2 cells at 5 uM measured after 2 hrs by LC-MS/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
5. | ALA5125549 | A | Apparent permeability across basal to apical side in human Caco-2 cells at 5 uM measured after 2 hrs by LC-MS/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA5125550 | A | Stability in human hepatocytes assessed as intrinsic clearance at 0.5 uM measured after 120 mins by LC/MS/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA5125551 | A | Stability in rat hepatocytes assessed as intrinsic clearance at 0.5 uM measured after 60 mins by LC/MS/MS analysis | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
8. | ALA5125552 | A | Stability in mouse hepatocytes assessed as intrinsic clearance at 0.5 uM measured after 60 mins by LC/MS/MS analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
9. | ALA5125594 | A | Drug recovery in iv dosed mouse feces | Mus musculus | 2 | organism-based format | Scientific Literature |