# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5125924 | B | Agonist activity at human KCNQ2 expressed in CHO cells assessed as fold increase in outward current at 10 uM at 50 mV by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
2. | ALA5125925 | B | Agonist activity at human KCNQ2 expressed in CHO cells assessed as increase in outward current at 50 mV by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
3. | ALA5125926 | B | Agonist activity at human KCNQ2 expressed in CHO cells assessed as increase in outward current at 0.3 to 10 uM at -90 to +60 mV by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
4. | ALA5125927 | B | Agonist activity at human KCNQ2 W236A mutant expressed in CHO cells assessed as increase in outward current at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
5. | ALA5125928 | B | Agonist activity at human KCNQ2 L299A mutant expressed in CHO cells assessed as increase in outward current at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
6. | ALA5125929 | B | Agonist activity at human KCNQ2 V302A mutant expressed in CHO cells assessed as increase in outward current at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
7. | ALA5125930 | B | Agonist activity at human KCNQ2 A306T mutant expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
8. | ALA5125931 | P | Lipophilicity, logD of the compound | 3 | ALA5120947 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA5125932 | B | Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
10. | ALA5125933 | B | Agonist activity at human KCNQ4 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
11. | ALA5125934 | B | Agonist activity at human KCNQ1 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
12. | ALA5125935 | B | Agonist activity at human KCNQ3 A316T mutant expressed in CHO cells assessed as increase in outward current at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
13. | ALA5125936 | B | Agonist activity at human KCNQ2/3 expressed in CHO cells assessed as increase in outward current at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
14. | ALA5125937 | B | Activation of human BKca expressed in HEK293T cells at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
15. | ALA5125938 | B | Activation of human Kv1.2 expressed in HEK293T cells at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
16. | ALA5125939 | B | Activation of human Kir4.1 expressed in HEK293T cells at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
17. | ALA5125940 | B | Activation of human TREK-1 channel expressed in CHO cells at 10 uM by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
18. | ALA5125942 | B | Agonist activity at human KCNQ2 expressed in CHO cells assessed as increase in outward current at 10 uM at 50 mV in presence of ztz240 by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature |