# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5123803 | Binding | Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 31 | ALA5120862 | protein complex format | Scientific Literature | |
2. | ALA5123804 | Binding | Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assay | Homo sapiens | 13 | ALA5120862 | protein complex format | Scientific Literature | |
3. | ALA5123805 | Binding | Inhibition of G9a (unknown origin) assessed as reduction in substrate methylation using histone H3 and SAM as substrate measured after 15 to 60 mins by microfluidic capillary electrophoresis analysis | Homo sapiens | 31 | ALA5120862 | single protein format | Scientific Literature | |
4. | ALA5123806 | Binding | Inhibition of DOTL1 (unknown origin) using [3H]SAM and HeLa oligo nucleosomes as substrates at 100 uM incubated for 1 hr relative to control | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
5. | ALA5123807 | Binding | Inhibition of DOTL1 (unknown origin) using [3H]SAM and HeLa oligo nucleosomes as substrates incubated for 1 hr | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
6. | ALA5123808 | Binding | Inhibition of SETD8 (unknown origin) using [3H]SAM and HeLa nucleosomes as substrates at 100 uM incubated for 1 hr relative to control | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
7. | ALA5123809 | Binding | Inhibition of SETD8 (unknown origin) using [3H]SAM and HeLa nucleosomes as substrates incubated for 1 hr | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
8. | ALA5123810 | Binding | Inhibition of EZH2 (unknown origin) using [3H]SAM and chicken core histone as substrates at 100 uM incubated for 1 hr relative to control | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
9. | ALA5123811 | Binding | Inhibition of EZH2 (unknown origin) using [3H]SAM and chicken core histone as substrates incubated for 1 hr | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
10. | ALA5123812 | Binding | Inhibition of PRMT1 (unknown origin) using [3H]SAM and chicken histone 4 as substrates at 100 uM incubated for 1 hr relative to control | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
11. | ALA5123813 | Binding | Inhibition of PRMT1 (unknown origin) using [3H]SAM and chicken histone 4 as substrates incubated for 1 hr | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
12. | ALA5123814 | Binding | Inhibition of human MAO-A using p-tyramine as substrate at 100 uM by fluorimetric analysis relative to control | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
13. | ALA5123815 | Binding | Inhibition of human MAO-A using p-tyramine as substrate by fluorimetric analysis | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
14. | ALA5123816 | Binding | Inhibition of human MAO-B using p-tyramine as substrate at 100 uM by fluorimetric analysis relative to control | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
15. | ALA5123817 | Binding | Inhibition of human MAO-B using p-tyramine as substrate by fluorimetric analysis | Homo sapiens | 6 | ALA5120862 | single protein format | Scientific Literature | |
16. | ALA5123818 | Functional | Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 9 | ALA5120862 | cell-based format | Scientific Literature | |
17. | ALA5123819 | Functional | Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 9 | ALA5120862 | cell-based format | Scientific Literature | |
18. | ALA5123820 | Functional | Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 144 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 9 | ALA5120862 | cell-based format | Scientific Literature | |
19. | ALA5123825 | Functional | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth at 0.2 to 2.5 uM incubated for 72 to 144 hrs by trypan blue staining based analysis | Homo sapiens | 4 | ALA5120862 | cell-based format | Scientific Literature | |
20. | ALA5123826 | Binding | Inhibition of LSD1 in human MV4-11 cells assessed as increase in H3K4me2 level at 0.2 to 2.5 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 7 | ALA5120862 | cell-based format | Scientific Literature |