# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5164477 | Binding | Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
2. | ALA5164478 | Binding | Agonist activity at AhR in human LS180 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
3. | ALA5164479 | Binding | Agonist activity at AhR in human LS180 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
4. | ALA5164481 | Binding | Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase reporter gene assay | Homo sapiens | 11 | ALA5154859 | cell-based format | Scientific Literature | |
5. | ALA5164485 | Binding | Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells assessed as relative efficacy incubated for 4 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 12 | ALA5154859 | cell-based format | Scientific Literature | |
6. | ALA5164486 | Binding | Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assay | Mus musculus | 3 | ALA5154859 | subcellular format | Scientific Literature | |
7. | ALA5164487 | Binding | Agonist activity at AhR in human LS180 cells assessed as induction of nuclear translocation at 1 uM incubated for 90 mins by DAPI staining based confocal fluorescence microscopic analysis | Homo sapiens | 2 | ALA5154859 | cell-based format | Scientific Literature | |
8. | ALA5164488 | Binding | Agonist activity at AhR in human LS180 cell lysates assessed as induction of AhR-ARNT heterodimerization at 1 uM incubated for 90 mins by co-immunoprecipitation assay | Homo sapiens | 2 | ALA5154859 | subcellular format | Scientific Literature | |
9. | ALA5164489 | Binding | Agonist activity at AhR in human LS180 cells assessed as binding of AhR to CYP1A1 promoter gene at 1 uM incubated for 90 mins by chromatin immunoprecipitation assay | Homo sapiens | 2 | ALA5154859 | cell-based format | Scientific Literature | |
10. | ALA5164490 | Binding | Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
11. | ALA5164491 | Binding | Agonist activity at AhR in human LS180 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
12. | ALA5164492 | Binding | Agonist activity at AhR in human LS180 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
13. | ALA5164493 | Binding | Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
14. | ALA5164494 | Binding | Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
15. | ALA5164495 | Binding | Agonist activity at AhR in human AZ-AHR reporter cell derived from human HepG2 cells assessed as increase in luciferase activity at 1 uM measured after 8 to 24 hrs | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
16. | ALA5164508 | Binding | Agonist activity at AhR in human HT-29 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
17. | ALA5164509 | Binding | Agonist activity at AhR in human HT-29 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature | |
18. | ALA5164510 | Binding | Agonist activity at AhR in AhR knockout human HT-29 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA5154859 | cell-based format | Scientific Literature |