# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5122025 | Functional | Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 10 | ALA5120786 | cell-based format | Scientific Literature | |
2. | ALA5122026 | Functional | Cytotoxicity against human MCF7 cells assessed as cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5120786 | cell-based format | Scientific Literature | |
3. | ALA5122027 | Functional | Cytotoxicity against human MCF-10A cells assessed as cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 19 | ALA5120786 | cell-based format | Scientific Literature | |
4. | ALA5122028 | Functional | Induction of cell cycle arrest in human HepG2 cells assessed as accumulation of cells at subG0/G1 phase at 4 uM by counting hypodiploid nuclei incubated for 72 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
5. | ALA5122029 | Functional | Induction of cell cycle arrest in human HepG2 cells assessed as accumulation of cells at G2/M phase at 4 uM incubated for 72 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
6. | ALA5122030 | Functional | Induction of cell cycle arrest in human HepG2 cells assessed as decrease in cyclin-B1 expression at 1.5 uM measured after 8 to 24 hrs by Western blotting analysis relative to control | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
7. | ALA5122031 | Functional | Induction of cell cycle arrest in human HepG2 cells assessed as decrease in cyclin-B1 expression at 1.5 uM measured after 72 hrs by Western blotting analysis relative to control | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
8. | ALA5122032 | Functional | Inhibition of cell migration in human HepG2 cells assessed as reduction in wound closure at 1.5 uM measured after 24 to 48 hrs by wound healing assay based contrat-phase microscopic analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
9. | ALA5122033 | Functional | Inhibition of cell invasion in human HepG2 cells assessed as reduction in MMP-9 level at 2.5 uM after 8 hrs by densitometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
10. | ALA5122034 | Functional | Inhibition of cell invasion in human HepG2 cells assessed as reduction in MMP-9 level at 2.5 uM after 72 hrs by densitometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
11. | ALA5122035 | Functional | Inhibition of cell invasion in human HepG2 cells assessed as reduction in MMP-2 level at 2.5 uM after 8 hrs by densitometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
12. | ALA5122036 | Functional | Inhibition of cell invasion in human HepG2 cells assessed as reduction in MMP-2 level at 2.5 uM after 24 hrs by densitometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
13. | ALA5122037 | Functional | Inhibition of cell invasion in human HepG2 cells assessed as reduction in MMP-2 level at 2.5 uM after 72 hrs by densitometric analysis | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
14. | ALA5122038 | Functional | Anticlonogenic activity against human HepG2 cells assessed as reduction of colony formation at 0.5 uM incubated for 14 days by crystal violet staining method | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
15. | ALA5122039 | Functional | Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs in presence of alpha-ketoglutarate by MTT assay | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
16. | ALA5122041 | Functional | Cytotoxicity against human U-87 MG cells overexpressing GLS-1 | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
17. | ALA5122042 | Functional | Cytotoxicity against human MIA PaCa-2 cells overexpressing GLS-1 | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
18. | ALA5122043 | Functional | Cytotoxicity against human SAOS-2 cells overexpressing GLS-1 | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
19. | ALA5122044 | Functional | Cytotoxicity against human A-375 cells overexpressing GLS-1 | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature | |
20. | ALA5122045 | Functional | Cytotoxicity against human A549 cells overexpressing GLS-1 | Homo sapiens | 1 | ALA5120786 | cell-based format | Scientific Literature |