# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5132035 | T | Cytotoxicity against human MRC9 cells assessed as cell viability incubated for 72 hrs by Cell titer- blue assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
2. | ALA5132036 | F | Cytotoxicity against human MV4-11 cells assessed as cell viability incubated for 72 hrs by Cell titer-blue assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
3. | ALA5132037 | B | Inhibition of recombinant full length human HDAC3 expressed in insect Sf9 cells by EMSA analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
4. | ALA5132038 | B | Inhibition of recombinant full length human HDAC6 expressed in insect Sf9 cells by EMSA analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
5. | ALA5132039 | B | Inhibition of recombinant full length human HDAC8 expressed in insect Sf9 cells by EMSA analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
6. | ALA5132040 | B | Inhibition of recombinant full length HDAC11 (unknown origin) expressed in insect Sf9 cells by EMSA analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
7. | ALA5132077 | P | Glutathione reactivity assessed as GSH adduct formation by LC/MS/MS analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA5158336 | F | Increase in acetylation of histone H3 in human MV4-11 cells at 0.1 uM after 6 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5158337 | B | Inhibition of full length human recombinant HDAC3 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring fluorescence intensity by EMSA method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
10. | ALA5158338 | B | Inhibition of full length human recombinant HDAC6 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring fluorescence intensity by EMSA method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
11. | ALA5158339 | B | Inhibition of full length human recombinant HDAC8 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring fluorescence intensity by EMSA method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
12. | ALA5158340 | B | Inhibition of full length human recombinant HDAC11 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring fluorescence intensity by EMSA method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
13. | ALA5158341 | B | Selectivity ratio of IC50 for full length human recombinant HDAC8 to IC50 for full length human recombinant HDAC6 | Homo sapiens | 16 | assay format | Scientific Literature | ||
14. | ALA5158342 | F | Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
15. | ALA5158343 | F | Cytotoxicity against human MM1.S cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
16. | ALA5158344 | T | Cytotoxicity against human MRC9 cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
17. | ALA5158356 | B | Competitive inhibition of N-terminal His-SUMO tagged zebra fish recombinant HDAC6 catalytic domain 2 transfected with pET28b(+) vector in Escherichia coli BL21 (DE3) RILP cells incubated for 10 mins followed by addition of FITC-M344 measured af ter 10 mins by fluorescence polarization assay | Danio rerio | 9 | assay format | Scientific Literature | ||
18. | ALA5158358 | T | Cytotoxicity against primary normal human fibroblast cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
19. | ALA5158359 | T | Cytotoxicity against HUVEC cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
20. | ALA5158362 | B | Binding affinity to full length HDAC6-NanoLuc fusion protein (unknown origin) expressed in HeLa cells assessed as residence time by NanoBRET assay | Homo sapiens | 9 | cell-based format | Scientific Literature |