# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5131088 | F | Induction of melanogenesis in mouse B16 cells assessed as increase in intracellular melanin content at 50 uM incubated for 49 hrs by NaOH lysis based microplate reader assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
2. | ALA5131089 | F | Induction of melanogenesis in mouse B16 cells assessed as increase in intracellular tyrosinase activity at 50 uM incubated for 48 hrs by L-DOPA oxidation method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
3. | ALA5131090 | F | Induction of melanogenesis in mouse B16 cells assessed as increase in intracellular melanin content at 1 to 50 uM incubated for 49 hrs by NaOH lysis based microplate reader assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA5131091 | F | Cytotoxicity against mouse B16 cells assessed as reduction in cell growth at 1 to 50 uM by CCK-8 assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA5131092 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of MITF protein expression at 50 uM incubated for 48 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA5131093 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of TYR protein expression at 50 uM incubated for 48 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA5131094 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of TRP-1 protein expression at 50 uM incubated for 48 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA5131095 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of TRP-2 protein expression at 50 uM incubated for 48 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA5131096 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of MITF mRNA expression at 50 uM by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA5131097 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of TYR mRNA expression at 50 uM by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA5131098 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of TRP-1 mRNA expression at 50 uM by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
12. | ALA5131099 | F | Induction of melanogenesis in mouse B16 cells assessed as upregulation of TRP-2 mRNA expression at 50 uM by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
13. | ALA5131100 | B | Inhibition of JAK/STAT signaling pathway in human HaCaT cells assessed as downregulation of IFN-gamma induced CXCL10 protein level at 1 to 50 uM incubated for 24 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5131101 | B | Inhibition of JAK/STAT signaling pathway in human HaCaT cells assessed as downregulation of IFN-gamma induced CXCL10 mRNA expression at 1 to 50 uM by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5131102 | B | Inhibition of JAK/STAT signaling pathway in human HaCaT cells assessed as downregulation of IFN-gamma induced JAK1 protein expression at 1 to 50 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA5131103 | B | Inhibition of JAK/STAT signaling pathway in human HaCaT cells assessed as downregulation of IFN-gamma induced JAK2 protein expression at 50 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA5131104 | B | Inhibition of JAK/STAT signaling pathway in human HaCaT cells assessed as downregulation of IFN-gamma induced p-STAT protein expression at 10 to 50 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |