#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5160026	F	In vivo antiplasmodial activity against Plasmodium falciparum 3D7 infected in humanized NSG SCID mouse malaria model assessed as parasitemia reduction at 5 mg/kg, po administered as single dose measured after 5 days by flow cytometric analysis	Plasmodium falciparum	1	ALA5154768	organism-based format	Scientific Literature
2.	ALA5160029	A	Cmax in Plasmodium falciparum 3D7-infected humanized NSG SCID mouse malaria model at 50 mg/kg, po administered as a single dose by LC-MS/MS analysis	Mus musculus	1	ALA5154768	organism-based format	Scientific Literature
3.	ALA5160030	A	Cmax in Plasmodium falciparum 3D7-infected humanized NSG SCID mouse malaria model at 5 mg/kg, po administered as a single dose by LC-MS/MS analysis	Mus musculus	1	ALA5154768	organism-based format	Scientific Literature
4.	ALA5160032	F	Antimalarial activity against Plasmodium falciparum 3D7 infected in human erythrocytes assessed as inhibition of parasite growth by SYBR Green-I dye based fluorescence analysis	Plasmodium falciparum	59	ALA5154768	organism-based format	Scientific Literature
5.	ALA5160033	T	Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ATP addition for 90 mins by luminescence based analysis	Homo sapiens	20	ALA5154768	assay format	Scientific Literature
6.	ALA5160034	P	Dissociation constant, pKa of the compound		20	ALA5154768	small-molecule physicochemical format	Scientific Literature
7.	ALA5160035	T	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo luminescent assay	Homo sapiens	3	ALA5154768	cell-based format	Scientific Literature
8.	ALA5160036	A	Chemical stability of the compound in FaSSIF assessed as compound degradation at 37 degreeC measured after 72 hrs		2	ALA5154768	small-molecule physicochemical format	Scientific Literature
9.	ALA5160037	A	Clearance in human liver microsomes	Homo sapiens	2	ALA5154768	microsome format	Scientific Literature
10.	ALA5160038	A	Clearance in rat liver microsomes	Rattus norvegicus	2	ALA5154768	microsome format	Scientific Literature
11.	ALA5160039	A	Clearance in mouse liver microsomes	Mus musculus	2	ALA5154768	microsome format	Scientific Literature
12.	ALA5160040	T	Inhibition of hERG by Qpatch-clamp method	Homo sapiens	19	ALA5154768	assay format	Scientific Literature
13.	ALA5160041	T	Binding affinity to human CDK7	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
14.	ALA5160042	T	Binding affinity to human FLT3	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
15.	ALA5160043	T	Binding affinity to human KIT	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
16.	ALA5160044	T	Binding affinity to human PIM1	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
17.	ALA5160045	T	Binding affinity to human PIM2	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
18.	ALA5160046	T	Binding affinity to human PIM3	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
19.	ALA5160058	T	Binding affinity to human HASPIN	Homo sapiens	2	ALA5154768	assay format	Scientific Literature
20.	ALA5160070	F	In vivo antiplasmodial activity against Plasmodium falciparum 3D7 infected in humanized NSG SCID mouse malaria model assessed as parasitemia reduction at 50 mg/kg, po administered as single dose measured after 5 days by flow cytometric analysis	Plasmodium falciparum	1	ALA5154768	organism-based format	Scientific Literature