The store will not work correctly when cookies are disabled.
The page will load shortly, Thanks for your patience!
| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source |
| 1. | ALA5136207 | B | Induction of BTK degradation in human MINO cells at 100 nM measured after 8 hrs by proteomic analysis | Homo sapiens | 1 | ALA5131541 | cell-based format | Scientific Literature |
| 2. | ALA5136208 | A | Half life in ICR mouse at 100 mg/kg, po measured upto 48 hrs by LC/MS analysis | Mus musculus | 2 | ALA5131541 | organism-based format | Scientific Literature |
| 3. | ALA5136209 | A | Half life in Sprague-Dawley rat at 5 to 10 mg/kg, po administered as cassette dose measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 22 | ALA5131541 | organism-based format | Scientific Literature |
| 4. | ALA5136210 | A | Tmax in Sprague-Dawley rat at 5 to 10 mg/kg, po administered as cassette dose measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 22 | ALA5131541 | organism-based format | Scientific Literature |
| 5. | ALA5136211 | A | Cmax in Sprague-Dawley rat at 5 to 10 mg/kg, po administered as cassette dose measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 22 | ALA5131541 | organism-based format | Scientific Literature |
| 6. | ALA5136212 | A | AUC (0 to t) in Sprague-Dawley rat at 5 to 10 mg/kg, po administered as cassette dose measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 30 | ALA5131541 | organism-based format | Scientific Literature |
| 7. | ALA5136213 | A | Dose normalized AUC (0 to t) in Sprague-Dawley rat at 5 to 10 mg/kg, po administered as cassette dose measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 22 | ALA5131541 | organism-based format | Scientific Literature |
| 8. | ALA5136220 | A | MRT in ICR mouse at 2 mg/kg, iv measured upto 48 hrs by LC/MS analysis | Mus musculus | 1 | ALA5131541 | organism-based format | Scientific Literature |
| 9. | ALA5136226 | A | Volume of distribution at steady state in ICR mouse at 2 mg/kg, iv measured upto 48 hrs by LC/MS analysis | Mus musculus | 1 | ALA5131541 | organism-based format | Scientific Literature |
| 10. | ALA5136227 | A | Clearance in ICR mouse at 2 mg/kg, iv measured upto 48 hrs by LC/MS analysis | Mus musculus | 1 | ALA5131541 | organism-based format | Scientific Literature |
| 11. | ALA5136228 | A | Oral bioavailability in ICR mouse at 100 mg/kg measured upto 48 hrs by LC/MS analysis | Mus musculus | 1 | ALA5131541 | organism-based format | Scientific Literature |
| 12. | ALA5136229 | A | Tmax in ICR mouse at 100 mg/kg, po measured upto 48 hrs by LC/MS analysis | Mus musculus | 2 | ALA5131541 | organism-based format | Scientific Literature |
| 13. | ALA5136230 | A | Cmax in ICR mouse at 100 mg/kg, po measured upto 48 hrs by LC/MS analysis | Mus musculus | 2 | ALA5131541 | organism-based format | Scientific Literature |
| 14. | ALA5136231 | A | AUC (0 to t) in ICR mouse at 100 mg/kg, po measured upto 48 hrs by LC/MS analysis | Mus musculus | 2 | ALA5131541 | organism-based format | Scientific Literature |
| 15. | ALA5136232 | A | AUC (0 to infinity) in ICR mouse at 100 mg/kg, po measured upto 48 hrs by LC/MS analysis | Mus musculus | 2 | ALA5131541 | organism-based format | Scientific Literature |
| 16. | ALA5136234 | B | Inhibition of BTK C481S mutant (unknown origin) | Homo sapiens | 1 | ALA5131541 | single protein format | Scientific Literature |
| 17. | ALA5136236 | F | Antiproliferative activity against human OCILY10 cells assessed as inhibition of cell growth incubated for 3 to 7 days by MTS assay | Homo sapiens | 4 | ALA5131541 | cell-based format | Scientific Literature |
| 18. | ALA5136238 | F | Antiproliferative activity against human TMD8 cells assessed as inhibition of cell growth incubated for 3 to 7 days by MTS assay | Homo sapiens | 4 | ALA5131541 | cell-based format | Scientific Literature |
| 19. | ALA5136239 | F | Antiproliferative activity against CRBN knockout human JeKo-1 cells assessed as inhibition of cell growth incubated for 3 to 7 days by MTS assay | Homo sapiens | 7 | ALA5131541 | cell-based format | Scientific Literature |
| 20. | ALA5136240 | F | Antiproliferative activity against human JeKo-1 cells assessed as inhibition of cell growth incubated for 3 to 7 days by MTS assay | Homo sapiens | 7 | ALA5131541 | cell-based format | Scientific Literature |