| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5144979 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as accumulation of norfloxacin at 3.9 ug/ml by measuring fluorescence intensity measured at 5 mins interval for 40 mins by fluorescence spectrophotometry | Staphylococcus aureus | 7 | single protein format | Scientific Literature | ||
| 2. | ALA5144980 | F | Antibacterial activity against Staphylococcus aureus 1199B measured after 24 hrs by Muller Hinton broth based MTT assay | Staphylococcus aureus | 32 | organism-based format | Scientific Literature | ||
| 3. | ALA5144981 | F | Antibacterial activity against Staphylococcus aureus 1199 measured after 24 hrs by Muller Hinton broth based MTT assay | Staphylococcus aureus | 29 | organism-based format | Scientific Literature | ||
| 4. | ALA5144982 | F | Antibacterial activity against Staphylococcus aureus K1758 measured after 24 hrs by Muller Hinton broth based MTT assay | Staphylococcus aureus | 29 | organism-based format | Scientific Literature | ||
| 5. | ALA5144983 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of norfloxacin-induced antibacterial activity by measuring Norfloxacin MIC at sub MIC | Staphylococcus aureus | 10 | single protein format | Scientific Literature | ||
| 6. | ALA5144984 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of norfloxacin-induced antibacterial activity by measuring Norfloxacin MIC at sub MIC relative to norfloxacin MIC alone | Staphylococcus aureus | 10 | single protein format | Scientific Literature | ||
| 7. | ALA5144985 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of norfloxacin-induced antibacterial activity by measuring fractional inhibitory concentration | Staphylococcus aureus | 10 | single protein format | Scientific Literature | ||
| 8. | ALA5144986 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of ethidium bromide-induced antibacterial activity by measuring ethidium bromide MIC at sub MIC | Staphylococcus aureus | 10 | single protein format | Scientific Literature | ||
| 9. | ALA5144987 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of ethidium bromide-induced antibacterial activity by measuring ethidium bromide MIC at sub MIC relative to ethidium bromide MIC alone | Staphylococcus aureus | 10 | single protein format | Scientific Literature | ||
| 10. | ALA5144988 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of ethidium bromide-induced antibacterial activity by measuring fractional inhibitory concentration | Staphylococcus aureus | 10 | single protein format | Scientific Literature | ||
| 11. | ALA5144989 | B | Inhibition of NorA in Staphylococcus aureus 1199 assessed as potentiation of norfloxacin-induced antibacterial activity | Staphylococcus aureus | 17 | single protein format | Scientific Literature | ||
| 12. | ALA5144990 | B | Inhibition of NorA in Staphylococcus aureus 1199 assessed as potentiation of ethidium bromide-induced antibacterial activity | Staphylococcus aureus | 17 | single protein format | Scientific Literature | ||
| 13. | ALA5144991 | B | Inhibition of NorA in Staphylococcus aureus K1758 assessed as potentiation of norfloxacin-induced antibacterial activity | Staphylococcus aureus | 17 | single protein format | Scientific Literature | ||
| 14. | ALA5144992 | B | Inhibition of NorA in Staphylococcus aureus K1758 assessed as potentiation of ethidium bromide-induced antibacterial activity | Staphylococcus aureus | 17 | single protein format | Scientific Literature | ||
| 15. | ALA5144996 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of 3.1 ug/mL norfloxacin-induced bactericidal activity by measuring log reduction in bacterial count at 7.8 ug/mL measured after 8 hrs by time-kill kinetics assay | Staphylococcus aureus | 3 | single protein format | Scientific Literature | ||
| 16. | ALA5145005 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of ethidium bromide-induced bactericidal activity at 7.8 ug/ml measured after 24 hrs by time-kill kinetics assay | Staphylococcus aureus | 2 | single protein format | Scientific Literature | ||
| 17. | ALA5145007 | T | Cytotoxicity against kidney epithelial cells (unknown origin) assessed as cell viability at 50 ug/mL measured after 24 hrs by alamar blue assay relative to control | Not specified | 8 | cell-based format | Scientific Literature | ||
| 18. | ALA5145009 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as potentiation of norfloxacin-induced morphological changes by measuring appearance of plicated and with cracked surface at sub MIC by field emission scanning electron microscopy | Staphylococcus aureus | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5145015 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as accumulation of ethidium bromide at 3.9 ug/ml by measuring fluorescence intensity measured at 5 mins interval for 40 mins by fluorescence spectrophotometry | Staphylococcus aureus | 8 | single protein format | Scientific Literature | ||
| 20. | ALA5145019 | F | Up regulation of NorA gene expression in Staphylococcus aureus 1199B at 3.9 ug/ml measured after 2 hrs by qRT-PCR analysis relative to control | Staphylococcus aureus | 1 | assay format | Scientific Literature |
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