#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5147326	F	Anti-necroptic activity in human HT-29 cells assessed as inhibition of TSZ induced necroptosis measured after 16 to 24 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	36	ALA5143660	cell-based format	Scientific Literature
2.	ALA5147327	T	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability	Homo sapiens	38	ALA5143660	cell-based format	Scientific Literature
3.	ALA5147328	B	Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system incubated for 1 hr under shaking condition by Kinomescan method	Homo sapiens	8	ALA5143660	assay format	Scientific Literature
4.	ALA5147329	F	Anti-necroptic activity in human HT-29 cells assessed as inhibition of TSZ induced necroptosis measured after 12 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
5.	ALA5147330	F	Anti-necroptic activity in human HT-29 cells assessed as inhibition of TCZ induced necroptosis measured after 16 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
6.	ALA5147331	F	Anti-necroptic activity in human U-937 cells assessed as inhibition of TSZ induced necroptosis pretreated with compound followed by TSZ addition ans measured after 12 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
7.	ALA5147332	F	Anti-necroptic activity in mouse L929 cells assessed as inhibition of TZ induced necroptosis pretreated with compound followed by TZ addition and measured after 12 hrs by celltiter-glo luminescent cell viability assay	Mus musculus	2	ALA5143660	cell-based format	Scientific Literature
8.	ALA5147333	F	Antiapoptotic activity in human HT-29 cells assessed as inhibition of TC induced apoptosis at 0.078 to 10 uM incubated for 36 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
9.	ALA5147334	F	Antiapoptotic activity in human HT-29 cells assessed as inhibition of TS induced apoptosis at 0.078 to 10 uM incubated for 24 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
10.	ALA5147335	B	Inhibition of RIPK1 phosphorylation in TSZ-induced human HT-29 cells pretreated with compound followed by TSZ stimulation and measured after 6 hrs by immunoblotting analysis	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
11.	ALA5147336	B	Inhibition of RIPK3 phosphorylation in TSZ-induced human HT-29 cells pretreated with compound followed by TSZ stimulation and measured after 6 hrs by immunoblotting analysis	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
12.	ALA5147337	B	Inhibition of MLKL phosphorylation in TSZ-induced human HT-29 cells pretreated with compound followed by TSZ stimulation and measured after 6 hrs by immunoblotting analysis	Homo sapiens	2	ALA5143660	cell-based format	Scientific Literature
13.	ALA5147341	B	Inhibition of RIPK1 phosphorylation in TSZ-induced human HT-29 cells at 20 nM pretreated with compound followed by TSZ stimulation and measured after 2 to 6 hrs by immunoblotting analysis	Homo sapiens	1	ALA5143660	cell-based format	Scientific Literature
14.	ALA5147342	B	Inhibition of RIPK3 phosphorylation in TSZ-induced human HT-29 cells at 20 nM pretreated with compound followed by TSZ stimulation and measured after 2 to 6 hrs by immunoblotting analysis	Homo sapiens	1	ALA5143660	cell-based format	Scientific Literature
15.	ALA5147343	B	Inhibition of downstream MLKL phosphorylation in TSZ-induced human HT-29 cells at 20 nM pretreated with compound followed by TSZ stimulation and measured after 2 to 6 hrs by immunoblotting analysis	Homo sapiens	1	ALA5143660	cell-based format	Scientific Literature
16.	ALA5147344	B	Inhibition of RIPK1-RIPK3-MLKL pathway in TSZ induced human HT-29 cells assessed as reduction in necrosome formation at 20 nM measured after 6 hrs by Western blot analysis	Homo sapiens	1	ALA5143660	cell-based format	Scientific Literature
17.	ALA5147347	F	Anti-necroptic activity against mTNFalpha-induced systemic inflammatory response syndrome C57BL/6J mouse model assessed as protection of body temperature pretreated with compound at 5 to 20 mg/kg, IG administered as single dose followed by mTNFalpha injection measured after 2 to 3 hrs	Mus musculus	1	ALA5143660	organism-based format	Scientific Literature
18.	ALA5147351	F	Anti-necroptic activity against mTNFalpha induced C57BL/6J mouse systemic inflammatory response syndrome model assessed as survival rate pretreated with compound at 5 to 20 mg/kg, IG administered as single dose followed by mTNFalpha injection and measured over 60 hrs	Mus musculus	1	ALA5143660	organism-based format	Scientific Literature
19.	ALA5147355	B	Inhibition of RIPK1 phosphorylation in TSZ-induced human HT-29 cells at 5 to 20 nM pretreated with compound followed by TSZ stimulation and measured after 6 hrs by immunoblotting analysis	Homo sapiens	1	ALA5143660	cell-based format	Scientific Literature
20.	ALA5147356	B	Inhibition of RIPK3 phosphorylation in TSZ-induced human HT-29 cells at 5 to 20 nM pretreated with compound followed by TSZ stimulation and measured after 6 hrs by immunoblotting analysis	Homo sapiens	1	ALA5143660	cell-based format	Scientific Literature