| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5113119 | B | Inhibition of human recombinant CYP4A11 using Luciferin-4A as substrate incubated for 60 mins in presence of NADPH regenerating system by luminescence based assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 2. | ALA5113120 | B | Inhibition of human recombinant CYP4F2 using Luciferin-4F2/3 as substrate incubated for 60 mins in presence of NADPH regenerating system by luminescence based assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 3. | ALA5113121 | P | Lipophilicity, log D of the compound at pH 7.4 by HPLC analysis | 16 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5113122 | A | Inhibition of CYP1A2 in human liver microsomes at 10 uM using phenacetin as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 5. | ALA5113123 | A | Inhibition of CYP2B6 in human liver microsomes at 10 uM using bupropion as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 6. | ALA5113124 | A | Inhibition of CYP2C8 in human liver microsomes at 10 uM using amodiaquine as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 7. | ALA5113125 | A | Inhibition of CYP2C9 in human liver microsomes at 10 uM using diclofenac as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 8. | ALA5113126 | A | Inhibition of CYP2C19 in human liver microsomes at 10 uM using mephenytoin as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 9. | ALA5113127 | A | Inhibition of CYP2D6 in human liver microsomes at 10 uM using bufuralol as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 10. | ALA5113128 | A | Inhibition of CYP3A4 in human liver microsomes at 10 uM using midazolam as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 11. | ALA5113129 | A | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate at 10 uM preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 12. | ALA5113130 | P | Thermodynamic solubility of the compound in phosphate buffer at pH 6.8 incubated for 24 hrs by HPLC analysis | 15 | small-molecule physicochemical format | Scientific Literature |
The page will load shortly, Thanks for your patience!