| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5155947 | P | Aqueous solubility of compound at pH 7.4 | 3 | ALA5154659 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA5155948 | A | Oral bioavailability in Wistar rat at 10 mg/kg | Rattus norvegicus | 2 | ALA5154659 | organism-based format | Scientific Literature | |
| 3. | ALA5155949 | T | Inhibition of human ERG | Homo sapiens | 3 | ALA5154659 | assay format | Scientific Literature | |
| 4. | ALA5155950 | A | Half life in Wistar rat at 0.5 mg/kg, iv | Rattus norvegicus | 3 | ALA5154659 | organism-based format | Scientific Literature | |
| 5. | ALA5155951 | B | Binding affinity to human adenosine A1A receptor expressed in human HEK293 cell membrane at 10 uM by radioligand inhibition assay | Homo sapiens | 28 | ALA5154659 | cell membrane format | Scientific Literature | |
| 6. | ALA5155953 | B | Binding affinity to human adenosine A2A receptor expressed in human HEK293 cell membrane at 10 uM by radioligand inhibition assay | Homo sapiens | 24 | ALA5154659 | cell membrane format | Scientific Literature | |
| 7. | ALA5155957 | B | Displacement of [125I] N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3A receptor stably expressed in HEK293 cell membrane by radioligand inhibition assay | Homo sapiens | 31 | ALA5154659 | cell membrane format | Scientific Literature | |
| 8. | ALA5155962 | A | Stability of the compound in simulated intestinal fluid assessed as parent compound remaining at 120 mins | 3 | ALA5154659 | assay format | Scientific Literature | ||
| 9. | ALA5155963 | A | Stability of the compound in simulated gastric fluid assessed as parent compound remaining at 120 mins | 3 | ALA5154659 | assay format | Scientific Literature | ||
| 10. | ALA5155964 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 3 | ALA5154659 | single protein format | Scientific Literature | |
| 11. | ALA5155965 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 3 | ALA5154659 | single protein format | Scientific Literature | |
| 12. | ALA5155966 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 3 | ALA5154659 | single protein format | Scientific Literature | |
| 13. | ALA5155967 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 3 | ALA5154659 | single protein format | Scientific Literature | |
| 14. | ALA5155968 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 3 | ALA5154659 | single protein format | Scientific Literature | |
| 15. | ALA5155969 | A | Stability in human plasma assessed as parent compound remaining measured after 120 mins | Homo sapiens | 3 | ALA5154659 | cell-free format | Scientific Literature | |
| 16. | ALA5155970 | A | Stability in Wistar rat plasma assessed as parent compound remaining measured after 120 mins | Rattus norvegicus | 3 | ALA5154659 | cell-free format | Scientific Literature | |
| 17. | ALA5155971 | A | Stability in mouse plasma assessed as parent compound remaining measured after 120 mins | Mus musculus | 3 | ALA5154659 | cell-free format | Scientific Literature | |
| 18. | ALA5155972 | A | Apparent permeability across apical to basolateral side in human Caco-2 cells | Homo sapiens | 3 | ALA5154659 | cell-based format | Scientific Literature | |
| 19. | ALA5155973 | A | Efflux ratio of permeability in human Caco2 cells | Homo sapiens | 3 | ALA5154659 | cell-based format | Scientific Literature | |
| 20. | ALA5155974 | A | Microsomal stability in mouse plasma assessed as half life | Mus musculus | 3 | ALA5154659 | cell-free format | Scientific Literature |
The page will load shortly, Thanks for your patience!