# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5147694 | B | Inhibition of recombinant human Nav 1.7 expressed in HEK293F cells incubated for 3 mins by FRET based membrane potential assay | Homo sapiens | 49 | cell membrane format | Scientific Literature | ||
2. | ALA5147695 | T | Inhibition of hERG channel by electrophysiology | Homo sapiens | 48 | assay format | Scientific Literature | ||
3. | ALA5147696 | A | Metabolic stability in human liver microsomes assessed as unbound intrinsic clearance at 0.5 uM measured upto 30 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 19 | microsome format | Scientific Literature | ||
4. | ALA5147697 | A | Metabolic stability in rat liver microsomes assessed as unbound intrinsic clearance at 0.5 uM measured upto 30 mins in the presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 19 | microsome format | Scientific Literature | ||
5. | ALA5147699 | P | Solubility of the compound in phosphate buffer by high throughput method | 43 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA5147701 | A | Permeability of the compound in MDCK cells | Canis lupus familiaris | 20 | cell-based format | Scientific Literature |