# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5099769 | F | Bactericidal activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as inhibition of bacterial growth at 4 to 16 ug/ml measured upto 24 hrs by time-kill assay | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
2. | ALA5099770 | F | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition after 14 to 16 hrs by CLSI based broth dilution method | Staphylococcus aureus | 13 | ALA5096228 | organism-based format | Scientific Literature | |
3. | ALA5099771 | F | Antimicrobial activity against Enterococcus faecium assessed as growth inhibition after 14 to 16 hrs by CLSI based broth dilution method | Enterococcus faecium | 13 | ALA5096228 | organism-based format | Scientific Literature | |
4. | ALA5099772 | F | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition after 14 to 16 hrs by CLSI based broth dilution method | Staphylococcus aureus | 13 | ALA5096228 | organism-based format | Scientific Literature | |
5. | ALA5099773 | F | Antimicrobial activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as growth inhibition after 14 to 16 hrs by CLSI based broth dilution method | Enterococcus faecium | 13 | ALA5096228 | organism-based format | Scientific Literature | |
6. | ALA5099774 | T | Cytotoxicity against mouse LLC cells assessed as reduction in cell viability | Mus musculus | 13 | ALA5096228 | cell-based format | Scientific Literature | |
7. | ALA5099775 | T | Hemolytic activity in human RBC at 50 ug/ml | Homo sapiens | 13 | ALA5096228 | cell-based format | Scientific Literature | |
8. | ALA5099776 | F | Induction of membrane disruption in Vancomycin-resistant Enterococcus faecium ATCC 51559 at 4 to 16 ug/ml measured after 15 mins by DiSC2(5) dye based multimode plate reader assay | Enterococcus faecium | 1 | ALA5096228 | subcellular format | Scientific Literature | |
9. | ALA5099777 | F | Induction of reactive oxygen species generation in Enterococcus faecium ATCC 51559 incubated for 1 hr by DCFH-DA based fluorescent microscopy | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
10. | ALA5099778 | A | Induction of membrane-permeabilization in Enterococcus faecium ATCC 51559 at 4 ug/ml measured after 1 hr by PI staining based flow cytometry analysis | Enterococcus faecium | 1 | ALA5096228 | assay format | Scientific Literature | |
11. | ALA5099779 | F | Induction of membrane-permeabilization in Enterococcus faecium ATCC 51559 at 8 ug/ml measured after 1 hr by PI staining based flow cytometry analysis | Enterococcus faecium | 1 | ALA5096228 | assay format | Scientific Literature | |
12. | ALA5099780 | F | Membrane permeabilization in Enterococcus faecium ATCC 51559 at 16 ug/ml measured after 1 hr by PI staining based flow cytometry analysis | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
13. | ALA5099781 | B | Disruption of membrane in Enterococcus faecium ATCC 51559 at 4 to 16 ug/ml measured after 1 hr by SYTO9/PI staining based fluorometric analysis | Enterococcus faecium | 1 | ALA5096228 | subcellular format | Scientific Literature | |
14. | ALA5099782 | B | Disruption of membrane in Enterococcus faecium ATCC 51559 at 4 ug/ml by SYTO9/PI staining based fluorometric analysis | Enterococcus faecium | 1 | ALA5096228 | subcellular format | Scientific Literature | |
15. | ALA5099783 | F | Antibiofilm activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as log reduction in colony forming unit incubated for 12 hrs by SYTO9 and PI staining based fluorescence assay | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
16. | ALA5099784 | F | Antibiofilm activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as log reduction in colony forming unit at 16 ug/ml incubated for 12 hrs by SYTO9 and PI staining based fluorescence assay | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
17. | ALA5099785 | F | Antibiofilm activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as log reduction in colony forming unit at 32 ug/ml incubated for 12 hrs by SYTO9 and PI staining based fluorescence assay | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
18. | ALA5099786 | F | Antibiofilm activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as log reduction in colony forming unit at 16 ug/ml by SYTO9 and PI staining based fluorescence assay | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
19. | ALA5099787 | F | Antibiofilm activity against Vancomycin-resistant Enterococcus faecium ATCC 51559 assessed as log reduction in colony forming unit at 16 ug/ml incubated for 3 hrs by SYTO9 and PI staining based fluorescence assay | Enterococcus faecium | 1 | ALA5096228 | organism-based format | Scientific Literature | |
20. | ALA5099788 | F | Immunostimulatory activity in BALB/c mouse assessed as change in neutrophil count in skin at 40 mg/kg administered topically 3 times daily for 6 days by flow cytometry analysis | Mus musculus | 1 | ALA5096228 | organism-based format | Scientific Literature |