# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5131230 | Binding | Inhibition of RyR2 in Casq2 gene knockout mouse cardiomyocytes assessed as reduction in calcium sparks frequency at 25 uM incubated for 15 mins by calcium sparks assay | Mus musculus | 10 | ALA5126670 | cell-based format | Scientific Literature | |
2. | ALA5229234 | Binding | Inhibition of RyR2 in Casq2 gene knockout mouse cardiomyocytes assessed as reduction in calcium sparks frequency at 25 uM incubated for 10 mins | Mus musculus | 6 | ALA5226356 | cell-based format | Scientific Literature | |
3. | ALA5229236 | Binding | Inhibition of RyR2 in Casq2 gene knockout mouse cardiomyocytes assessed as reduction in calcium sparks frequency incubated for 30 mins | Mus musculus | 2 | ALA5226356 | cell-based format | Scientific Literature | |
4. | ALA5229237 | Physicochemical | Kinetic solubility of the compound in phosphate buffer at pH 7.4 at 25 uM incubated for 2 hrs by nephelometry | 6 | ALA5226356 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA5229238 | ADME | Kinetic solubility of the compound in Hanks Bile Salt Solution at 25 uM incubated for 2 hrs by nephelometry | 6 | ALA5226356 | assay format | Scientific Literature |