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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5142716 F Anti-filarial activity against Onchocerca gutturosa adult worms assessed as reduction in worm motility measured every 24 hrs for 5 days by olympus inverted microscopic analysis Onchocerca gutturosa 60 organism-based format Scientific Literature 2. ALA5142717 P Kinetic solubility of compound incubated for 24 hrs 59 small-molecule physicochemical format Scientific Literature 3. ALA5142724 P Octanol/water distribution coefficient, logD of the compound at pH 7.4 sonicated for 30 mins followed by 24 hrs shaking 53 small-molecule physicochemical format Scientific Literature 4. ALA5142725 A Apparent permeability of compound across apical to basolateral in MDCK-II cells expressing human P-glycoprotein gene at 10 uM measured at 2 hrs by LC-MS/MS analysis Canis lupus familiaris 12 cell-based format Scientific Literature 5. ALA5142726 A Efflux ratio of apparent permeability in MDCK-II cells expressing human P-glycoprotein gene at 10 uM measured at 2 hrs by LC-MS/MS analysis Canis lupus familiaris 12 cell-based format Scientific Literature 6. ALA5142734 F Antiparasitic activity against Litomosoides sigmodontis infected in Meriones assessed as reduction in worm burden at 15 mg/kg, sc BID administered for 7 days Litomosoides sigmodontis 1 organism-based format Scientific Literature 7. ALA5142736 A Cmax in CD-1 mouse at 30 mg/kg, po measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 8 organism-based format Scientific Literature 8. ALA5142738 A Cmax in CD-1 mouse at 10 mg/kg, po measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 9. ALA5142739 A Tmax in CD-1 mouse at 30 mg/kg, po measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 8 organism-based format Scientific Literature 10. ALA5142741 A Tmax in CD-1 mouse at 10 mg/kg, po measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 11. ALA5142742 A AUC (0 to infinity) in CD-1 mouse at 30 mg/kg, po measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 8 organism-based format Scientific Literature 12. ALA5142744 A AUC (0 to infinity) in CD-1 mouse at 10 mg/kg, po measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 13. ALA5142745 A Clearance in CD-1 mouse at 2 mg/kg, iv measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 14. ALA5142746 A Volume of distribution at steady state in CD-1 mouse at 2 mg/kg, iv measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 15. ALA5142747 A Oral bioavailability in CD-1 mouse at 10 mg/kg measured at 0.5 to 8 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 16. ALA5142749 A Ratio of AUC (0 to t) in brain to plasma in BALB/c mouse at 30 mg/kg, po by LC-MS/MS analysis Mus musculus 1 organism-based format Scientific Literature 17. ALA5142751 A Plasma protein binding in human Homo sapiens 2 cell-free format Scientific Literature 18. ALA5142752 A Plasma protein binding in rat Rattus norvegicus 2 cell-free format Scientific Literature 19. ALA5142753 A Inhibition of CYP3A4 (unknown origin) Homo sapiens 2 single protein format Scientific Literature 20. ALA5142754 A Inhibition of CYP1A2 (unknown origin) Homo sapiens 2 single protein format Scientific Literature