# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5126420 | Binding | Agonist activity at human human NOD2 expressed in HEK-Blue NOD2 reporter cells by colorimetry based SEAP assay | Homo sapiens | 27 | ALA5120973 | cell-based format | Scientific Literature | |
2. | ALA5126421 | Binding | Agonist activity at human human NOD1 expressed in HEK-Blue NOD1 reporter cells at 2 uM by colorimetry based SEAP assay | Homo sapiens | 27 | ALA5120973 | cell-based format | Scientific Literature | |
3. | ALA5126422 | Binding | Agonist activity at human human NOD2 expressed in HEK-Blue NOD2 reporter cells in presence of NOD2 antagonist by colorimetry based SEAP assay | Homo sapiens | 27 | ALA5120973 | cell-based format | Scientific Literature | |
4. | ALA5126423 | Binding | Agonist activity at human mouse NOD2 expressed in RAW -Blue NOD2 reporter cells by colorimetry based SEAP assay | Mus musculus | 1 | ALA5120973 | cell-based format | Scientific Literature | |
5. | ALA5126424 | Binding | Agonist activity at human mouse NOD2 expressed in RAW -Blue NOD2 reporter cells in presence of NOD2 antagonist by colorimetry based SEAP assay | Mus musculus | 1 | ALA5120973 | cell-based format | Scientific Literature | |
6. | ALA5126425 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of IL-1beta production at 1 uM incubated for 18 hrs | Homo sapiens | 3 | ALA5120973 | cell-based format | Scientific Literature | |
7. | ALA5126426 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of IL-6 production at 1 uM incubated for 18 hrs | Homo sapiens | 3 | ALA5120973 | cell-based format | Scientific Literature | |
8. | ALA5126427 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of IL-8 production at 1 uM incubated for 18 hrs | Homo sapiens | 3 | ALA5120973 | cell-based format | Scientific Literature | |
9. | ALA5126428 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of TNFalpha production at 1 uM incubated for 18 hrs | Homo sapiens | 3 | ALA5120973 | cell-based format | Scientific Literature | |
10. | ALA5126429 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of IL-8 production at 1 uM incubated for 18 hrs pretreated with NOD2 antagonist | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
11. | ALA5126430 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of IL-1beta production at 1 uM incubated for 18 hrs pretreated with NOD2 antagonist | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
12. | ALA5126431 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of IL-6 production at 1 uM incubated for 18 hrs pretreated with NOD2 antagonist | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
13. | ALA5126432 | Binding | Agonist activity at NOD2 in human PBMC assessed as induction of TNFalpha production at 1 uM incubated for 18 hrs pretreated with NOD2 antagonist | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
14. | ALA5126433 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of IL-1beta production at 1 uM incubated for 18 hrs in presence of IFN-gamma | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
15. | ALA5126434 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of IL-6 production at 1 uM incubated for 18 hrs in presence of IFN-gamma | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
16. | ALA5126435 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of TNFalpha production at 1 uM incubated for 18 hrs in presence of IFN-gamma | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
17. | ALA5126436 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of IL-8 production at 1 uM incubated for 18 hrs in presence of IFN-gamma | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
18. | ALA5126437 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of IL-1beta production at 1 uM incubated for 18 hrs in presence of LPS | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
19. | ALA5126438 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of IL-6 production at 1 uM incubated for 18 hrs in presence of LPS | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature | |
20. | ALA5126439 | Binding | Synergistic agonist activity at NOD2 in human PBMC assessed as induction of TNF-alpha production at 1 uM incubated for 18 hrs in presence of LPS | Homo sapiens | 1 | ALA5120973 | cell-based format | Scientific Literature |