# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5117239 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 5 | microsome format | Scientific Literature | ||
2. | ALA5117240 | A | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 5 | microsome format | Scientific Literature | ||
3. | ALA5117241 | A | Metabolic stability in mouse liver microsomes assessed as half life | Mus musculus | 5 | microsome format | Scientific Literature | ||
4. | ALA5117242 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as bacterial growth inhibition incubated for 7 days by MABA assay | Mycobacterium tuberculosis | 9 | organism-based format | Scientific Literature | ||
5. | ALA5117243 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as bacterial growth inhibition incubated for 10 days under hypoxic condition followed by 28 hrs incubation under normoxic condition by Low-Oxygen-Recovery Assay | Mycobacterium tuberculosis | 5 | organism-based format | Scientific Literature | ||
6. | ALA5117244 | T | Cytotoxicity against African green monkey vero cells assessed as reduction in cell viability | Chlorocebus sabaeus | 9 | cell-based format | Scientific Literature | ||
7. | ALA5117245 | A | Clearance in CD-1 mouse at 0.6 mg/kg, iv | Mus musculus | 5 | organism-based format | Scientific Literature | ||
8. | ALA5117246 | A | Volume of distribution in CD-1 mouse at 0.6 mg/kg, iv | Mus musculus | 5 | organism-based format | Scientific Literature | ||
9. | ALA5117247 | A | Half life in CD-1 mouse at 0.6 mg/kg, iv | Mus musculus | 5 | organism-based format | Scientific Literature | ||
10. | ALA5117248 | A | Cmax in CD-1 mouse at 5 mg/kg, po | Mus musculus | 5 | organism-based format | Scientific Literature | ||
11. | ALA5117249 | A | AUC (0-last) in CD-1 mouse at 5 mg/kg, po | Mus musculus | 5 | organism-based format | Scientific Literature | ||
12. | ALA5117250 | A | Oral bioavailability in CD-1 mouse at 5 mg/kg | Mus musculus | 5 | organism-based format | Scientific Literature | ||
13. | ALA5117251 | P | Aqueous solubility of compound at pH 2.0 | 2 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA5117252 | P | Aqueous solubility of compound at pH 7.4 | 2 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA5117253 | A | Apparent permeability across apical to basolateral side in dog MDCK cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
16. | ALA5117254 | A | Apparent permeability across basolateral to apical side in dog MDCK cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
17. | ALA5117255 | A | Efflux ratio of apparent permeability across basolateral to apical over apical to basolateral membrane in dog MDCK cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
18. | ALA5117256 | A | Plasma protein binding in mouse assessed as bound fraction | Mus musculus | 2 | cell-free format | Scientific Literature | ||
19. | ALA5117257 | A | Plasma protein binding in rat assessed as bound fraction | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
20. | ALA5117258 | A | Plasma protein binding in dog assessed as bound fraction | Canis lupus familiaris | 2 | cell-free format | Scientific Literature |