# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5142410 | F | Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 80 | ALA5137091 | cell membrane format | Scientific Literature | |
2. | ALA5142411 | B | Antagonist activity at human Galphai2-fused GPR84 Phe101Ala mutant stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA5137091 | cell membrane format | Scientific Literature | |
3. | ALA5142412 | B | Antagonist activity at human Galphai2-fused GPR84 Phe335Ala mutant stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA5137091 | cell membrane format | Scientific Literature | |
4. | ALA5142413 | B | Antagonist activity at human Galphai2-fused GPR84 Trp360Ala mutant stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 1 | ALA5137091 | cell membrane format | Scientific Literature | |
5. | ALA5142414 | F | Antagonist activity at human FFAR2 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of C3 fatty acid propionate-induced [35S]GTPgammaS binding at 10 uM preincubated for 15 mins followed by C3 fatty acid propionate addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 4 | ALA5137091 | cell membrane format | Scientific Literature | |
6. | ALA5142415 | F | Antagonist activity at human FFAR3 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of C3 fatty acid propionate-induced [35S]GTPgammaS binding at 10 uM preincubated for 15 mins followed by C3 fatty acid propionate addition and measured after 45 mins by liquid scintillation counting analysis | Homo sapiens | 4 | ALA5137091 | cell membrane format | Scientific Literature |