| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5159113 | F | Antitrypanosomal activity against Trypanosoma brucei incubated for 72 hrs by alamar blue dye based fluorimetry analysis | Trypanosoma brucei | 16 | organism-based format | Scientific Literature | ||
| 2. | ALA5159114 | F | Antileishmanial activity against Leishmania major (MHOM/IL/80/Friedlin) promastigotes assessed as reduction in parasite growth incubated for 72 hrs by MTT assay | Leishmania major | 16 | organism-based format | Scientific Literature | ||
| 3. | ALA5159115 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 4. | ALA5159116 | T | Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA5159117 | T | Selectivity index, ratio of IC50 for human MRC5 cells to IC50 for human HT-29 cells | 16 | assay format | Scientific Literature | |||
| 6. | ALA5159118 | T | Selectivity index, ratio of IC50 for cytotoxicity against human MRC5 cells to IC50 for antileishmanial activity against Leishmania major (MHOM/IL/80/Friedlin) promastigotes | 13 | cell-based format | Scientific Literature | |||
| 7. | ALA5159119 | T | Selectivity index, ratio of IC50 for cytotoxicity against human MRC5 cells to IC50 for antitrypanosomal activity against Trypanosoma brucei | 16 | cell-based format | Scientific Literature | |||
| 8. | ALA5159120 | B | Binding affinity to human G-quadruplex telomeric DNA F21T (5'-duplex GGG TTAGGG TTAGGG TTAGGG-3') assessed as change in melting temperature at 1 uM incubated for 5 min by FRET assay | Homo sapiens | 6 | nucleic acid format | Scientific Literature | ||
| 9. | ALA5159125 | A | Drug uptake in Trypanosoma brucei at 10 uM incubated for 2 hrs by fluorescence based multiplate reader method | Trypanosoma brucei | 10 | assay format | Scientific Literature | ||
| 10. | ALA5159129 | B | Binding affinity to human G-quadruplex telomeric DNA F21T (5'-duplex GGG TTAGGG TTAGGG TTAGGG-3') assessed as change in melting temperature at 5 uM incubated for 5 min by FRET assay | Homo sapiens | 1 | nucleic acid format | Scientific Literature |
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