# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5111457 | B | Inhibition of human wild type partial length PIKfyve (F1512 to C2098 residues) expressed in mammalian expression assessed as remaining activity at 1 uM by Kinomescan assay relative to control | Homo sapiens | 32 | ALA5108045 | assay format | Scientific Literature | |
2. | ALA5111458 | B | Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for 60 mins in presence of ATP by ADP-Glo assay | Homo sapiens | 22 | ALA5108045 | cell-based format | Scientific Literature | |
3. | ALA5111459 | B | Inhibition of PIKFYVE in HEK293 cells by NanoBRET assay | Homo sapiens | 34 | ALA5108045 | cell-based format | Scientific Literature | |
4. | ALA5236876 | B | Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP addition and further incubated for 120 mins by TR-FRET assay | Homo sapiens | 31 | ALA5236545 | single protein format | Scientific Literature | |
5. | ALA5236877 | B | Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assay | Homo sapiens | 23 | ALA5236545 | cell-based format | Scientific Literature | |
6. | ALA5236879 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in dog MDCK-MDR1 cells | Canis lupus familiaris | 24 | ALA5236545 | cell-based format | Scientific Literature |