| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5146161 | F | Anti-diabesity activity against db/db mouse assessed as reduction in HbA1c level at 25 nmol/kg, sc administered every 2 days and measured on day 43 | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA5146162 | F | Anti-diabesity activity against db/db mouse assessed as reduction in fasting blood glucose level at 25 nmol/kg, sc administered every 2 days for 12 weeks | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 3. | ALA5146163 | F | Anti-diabesity activity in DIO C57BL/6 mouse assessed as decrease in fasted blood glucose level at 100 nmol/kg, sc administered once daily for 7 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA5146164 | F | Agonist activity at human GLP-1R expressed in HEK293 cells assessed as cAMP release incubated for 20 min by HTRF analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA5146165 | F | Agonist activity at human CCK1R expressed in HEK293 cells assessed as ERK1/2 phosphorylation incubated for 5 mins by AlphaScreen assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA5146166 | T | Agonist activity at human CCK2R expressed in HEK293 cells assessed as ERK1/2 phosphorylation incubated for 5 mins by AlphaScreen assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA5146167 | A | Cmax in Sprague-Dawley rat at 25 nmol/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA5146168 | A | Half life in Sprague-Dawley rat at 25 nmol/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA5146169 | A | AUC (0 to infinity) in Sprague-Dawley rat at 25 nmol/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA5146170 | A | Cmax in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA5146171 | A | Half life in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA5146172 | A | MRT in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA5146173 | A | AUC (0 to infinity) in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA5146178 | F | Hypoglycemic activity in ICR mouse assessed as improvement in glucose tolerance at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 120 mins by OGTT | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 15. | ALA5146179 | F | Anorectic activity in ICR mouse assessed as decrease in food intake at 25 nmol/kg, ip and measured after 9 hrs | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 16. | ALA5146180 | F | Hypoglycemic activity in db/db mouse assessed as improvement in glucose tolerance at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 120 mins by OGTT | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 17. | ALA5146181 | F | Hypoglycemic activity in db/db mouse assessed as reduction in glucose excursion at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 120 mins by OGTT | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 18. | ALA5146182 | F | Insulinotropic activity in db/db mouse assessed as elevation of plasma insulin level at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 60 mins by ELISA | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 19. | ALA5146183 | F | Hypoglycemic activity in sc dosed non-fasted db/db mouse assessed as reduction in blood glucose level measured upto 48 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA5146184 | F | Anti-diabesity activity in DIO C57BL/6 mouse assessed as reduction in body weight at 10 nmol/kg, sc administered every 2 days for 10 days | Mus musculus | 4 | organism-based format | Scientific Literature |
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