# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5164596 | A | Cmax in ICR mouse at 15 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | ALA5154862 | organism-based format | Scientific Literature | |
2. | ALA5164597 | A | AUC in ICR mouse at 15 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | ALA5154862 | organism-based format | Scientific Literature | |
3. | ALA5164598 | A | Oral bioavailability in ICR mouse at 15 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 1 | ALA5154862 | organism-based format | Scientific Literature | |
4. | ALA5164599 | F | Upregulation of p21 protein expression in human U2OS cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
5. | ALA5164600 | F | Upregulation of MDM2 protein expression in human U2OS cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
6. | ALA5164601 | F | Upregulation of p53 protein expression in human U2OS cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
7. | ALA5164605 | F | Upregulation of p21 protein expression in human MCF7 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
8. | ALA5164606 | F | Upregulation of MDM2 protein expression in human MCF7 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
9. | ALA5164611 | F | Upregulation of MDM2 gene expression in human RKO cells at 0.31 uM incubated for 24 hrs by qPCR analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
10. | ALA5164612 | F | Upregulation of p53 protein expression in human MCF7 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
11. | ALA5164613 | F | Upregulation of p21 gene expression in human RKO cells at 0.31 uM incubated for 24 hrs by qPCR analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
12. | ALA5164614 | F | Upregulation of MDM2 protein expression in human NCI-H460 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
13. | ALA5164616 | F | Upregulation of p53 protein expression in human HCT-116 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
14. | ALA5164617 | F | Upregulation of MDM2 protein expression in human HCT-116 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
15. | ALA5164618 | F | Upregulation of p21 protein expression in human HCT-116 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
16. | ALA5164619 | F | Upregulation of p53 protein expression in human NCI-H460 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
17. | ALA5164620 | F | Upregulation of p21 protein expression in human NCI-H460 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
18. | ALA5164621 | F | Induction of cell cycle arrest in human RKO cells assessed as effect on cell cycle distribution incubated for 24 hrs by FACSCalibur flow cytometry analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
19. | ALA5164622 | F | Effect on MDM4 protein expression in human U2OS cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
20. | ALA5164624 | F | Effect on MDM4 protein expression in human MCF7 cells at 2.5 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature |