# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5127848 | F | Antitumor activity against human Pfeiffer cells xenografted in Scid-Beige mouse assessed as tumor growth inhibition at 300 mg/kg, sc, two times a week for 5 weeks relative to control | Homo sapiens | 1 | ALA5126528 | organism-based format | Scientific Literature | |
2. | ALA5127865 | B | Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assay | Homo sapiens | 2 | ALA5126528 | single protein format | Scientific Literature | |
3. | ALA5127867 | B | Binding affinity to GST-tagged EED (unknown origin) assessed as thermal stability by measuring melting temperature at 50 uM by TSA method | Homo sapiens | 1 | ALA5126528 | single protein format | Scientific Literature | |
4. | ALA5127868 | B | Binding affinity to GST-tagged EED (unknown origin) assessed as thermal stability by measuring melting temperature at 500 uM by TSA method | Homo sapiens | 1 | ALA5126528 | single protein format | Scientific Literature | |
5. | ALA5127869 | B | Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAM | Homo sapiens | 1 | ALA5126528 | protein complex format | Scientific Literature | |
6. | ALA5127870 | F | Reduction of H3K27me2 level in human rhabdoid tumor cell line | Homo sapiens | 1 | ALA5126528 | cell-based format | Scientific Literature | |
7. | ALA5127871 | F | Reduction of H3K27me3 level in human rhabdoid tumor cell line | Homo sapiens | 1 | ALA5126528 | cell-based format | Scientific Literature | |
8. | ALA5127872 | F | Antitumor activity against human DLBCL pfeiffer cells xenografted in mouse assessed as tumor growth inhibition at 300 mg/kg, sc administered twice per week for 5 weeks relative to control | Homo sapiens | 1 | ALA5126528 | organism-based format | Scientific Literature |