# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5162380 | Binding | Inhibition of ATM (unknown origin) by FRET assay | Homo sapiens | 35 | ALA5154812 | single protein format | Scientific Literature | |
2. | ALA5162382 | Binding | Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assay | Homo sapiens | 8 | ALA5154812 | cell-based format | Scientific Literature | |
3. | ALA5162383 | Binding | Inhibition of ATR (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
4. | ALA5162384 | Binding | Inhibition of mTOR (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
5. | ALA5162385 | Binding | Inhibition of DNA-PK (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
6. | ALA5162386 | Binding | Inhibition of LRRK2 (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
7. | ALA5162387 | Binding | Inhibition of PI3Kalpha (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
8. | ALA5162388 | Binding | Inhibition of PI3Kbeta (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
9. | ALA5162389 | Binding | Inhibition of PI3Kdelta (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
10. | ALA5162390 | Binding | Inhibition of PI3Kgamma (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 2 | ALA5154812 | single protein format | Scientific Literature | |
11. | ALA5162391 | ADME | Metabolic stability in mouse liver microsomes assessed as parent compound remaining after 120 mins | Mus musculus | 3 | ALA5154812 | microsome format | Scientific Literature | |
12. | ALA5162392 | Binding | Selectivity ratio for inhibition of ATR (unknown origin) to inhibition of ATM (unknown origin) | Homo sapiens | 2 | ALA5154812 | assay format | Scientific Literature |