# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5149726 | B | Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ethyl isopropyl amiloride by BCECF-AM dye based fluorescence assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
2. | ALA5149743 | F | In vivo inhibition of NEH3 in Sprague-Dawley rat assessed as fecal form score at 3 mg/kg, po administered via gavage measured after 6 hrs | Rattus norvegicus | 30 | organism-based format | Scientific Literature | ||
3. | ALA5149744 | F | In vivo inhibition of NEH3 in Sprague-Dawley rat assessed as fecal water content at 3 mg/kg, po administered via gavage measured after 6 hrs | Rattus norvegicus | 30 | organism-based format | Scientific Literature | ||
4. | ALA5149745 | F | In vivo inhibition of NEH3 in Sprague-Dawley rat assessed as sodium excretion in urine at 10 mg/kg, po administered via gavage measured after 6 hrs by ion chromatography relative to control | Rattus norvegicus | 30 | organism-based format | Scientific Literature |