# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5141669 | Binding | Protac activity at VHL E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation at 0.1 to 0.5 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5137075 | cell-based format | Scientific Literature | |
2. | ALA5141670 | Binding | Protac activity at VHL E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation at 2.5 to 10 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 4 | ALA5137075 | cell-based format | Scientific Literature | |
3. | ALA5141689 | Binding | Protac activity at VHL E3 ligase/GSPT1 in HEK293FT cells assessed as induction of NSD2 degradation at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5137075 | cell-based format | Scientific Literature | |
4. | ALA5141690 | Binding | Protac activity at VHL E3 ligase/IKZF3 in HEK293FT cells assessed as induction of IKZF3 degradation at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5137075 | cell-based format | Scientific Literature | |
5. | ALA5141691 | Binding | Protac activity at VHL E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human KMS-11 cells assessed as induction of NSD2 degradation at 5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA5137075 | cell-based format | Scientific Literature | |
6. | ALA5141692 | Binding | Protac activity at VHL E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human NCI-H929 cells assessed as induction of NSD2 degradation at 5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA5137075 | cell-based format | Scientific Literature |