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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5146161 F Anti-diabesity activity against db/db mouse assessed as reduction in HbA1c level at 25 nmol/kg, sc administered every 2 days and measured on day 43 Mus musculus 3 organism-based format Scientific Literature 2. ALA5146162 F Anti-diabesity activity against db/db mouse assessed as reduction in fasting blood glucose level at 25 nmol/kg, sc administered every 2 days for 12 weeks Mus musculus 3 organism-based format Scientific Literature 3. ALA5146163 F Anti-diabesity activity in DIO C57BL/6 mouse assessed as decrease in fasted blood glucose level at 100 nmol/kg, sc administered once daily for 7 days Mus musculus 2 organism-based format Scientific Literature 4. ALA5146164 F Agonist activity at human GLP-1R expressed in HEK293 cells assessed as cAMP release incubated for 20 min by HTRF analysis Homo sapiens 10 cell-based format Scientific Literature 5. ALA5146165 F Agonist activity at human CCK1R expressed in HEK293 cells assessed as ERK1/2 phosphorylation incubated for 5 mins by AlphaScreen assay Homo sapiens 10 cell-based format Scientific Literature 6. ALA5146166 T Agonist activity at human CCK2R expressed in HEK293 cells assessed as ERK1/2 phosphorylation incubated for 5 mins by AlphaScreen assay Homo sapiens 10 cell-based format Scientific Literature 7. ALA5146167 A Cmax in Sprague-Dawley rat at 25 nmol/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 8. ALA5146168 A Half life in Sprague-Dawley rat at 25 nmol/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 9. ALA5146169 A AUC (0 to infinity) in Sprague-Dawley rat at 25 nmol/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 10. ALA5146170 A Cmax in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 11. ALA5146171 A Half life in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA5146172 A MRT in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 13. ALA5146173 A AUC (0 to infinity) in Sprague-Dawley rat at 25 nmol/kg, sc by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 14. ALA5146179 F Anorectic activity in ICR mouse assessed as decrease in food intake at 25 nmol/kg, ip and measured after 9 hrs Mus musculus 8 organism-based format Scientific Literature 15. ALA5146180 F Hypoglycemic activity in db/db mouse assessed as improvement in glucose tolerance at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 120 mins by OGTT Mus musculus 4 organism-based format Scientific Literature 16. ALA5146181 F Hypoglycemic activity in db/db mouse assessed as reduction in glucose excursion at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 120 mins by OGTT Mus musculus 4 organism-based format Scientific Literature 17. ALA5146182 F Insulinotropic activity in db/db mouse assessed as elevation of plasma insulin level at 25 nmol/kg, ip administered 30 min before oral glucose administration and measured upto 60 mins by ELISA Mus musculus 4 organism-based format Scientific Literature 18. ALA5146183 F Hypoglycemic activity in sc dosed non-fasted db/db mouse assessed as reduction in blood glucose level measured upto 48 hrs Mus musculus 2 organism-based format Scientific Literature 19. ALA5146184 F Anti-diabesity activity in DIO C57BL/6 mouse assessed as reduction in body weight at 10 nmol/kg, sc administered every 2 days for 10 days Mus musculus 4 organism-based format Scientific Literature 20. ALA5146185 F Anti-diabesity activity in DIO C57BL/6 mouse assessed as reduction in body weight at 25 nmol/kg, sc administered every 2 days for 10 days Mus musculus 4 organism-based format Scientific Literature