# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5118008 | F | Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
2. | ALA5118009 | F | Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
3. | ALA5118010 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
4. | ALA5118011 | F | Antiproliferative activity against human SK-OV-3 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
5. | ALA5118012 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
6. | ALA5118013 | F | Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
7. | ALA5118014 | F | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
8. | ALA5118015 | F | Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell growth | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
9. | ALA5118016 | F | Antiproliferative activity against mouse 4T1 cells assessed as inhibition of cell growth | Mus musculus | 2 | ALA5113488 | cell-based format | Scientific Literature | |
10. | ALA5118017 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth pretreated with hENT1 inhibitor, dipyridamole at 10 uM followed by compound addition | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
11. | ALA5118018 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated in presence of 10 uM imatinib | Homo sapiens | 2 | ALA5113488 | cell-based format | Scientific Literature | |
12. | ALA5118019 | F | Induction of DNA damage in human MDA-MB-231 cells assessed as increase in phospho-gamma-H2A.X expression level at 0.3 to 3 uM | Homo sapiens | 1 | ALA5113488 | cell-based format | Scientific Literature | |
13. | ALA5118022 | A | Inhibition of CYP3A2 in rat liver microsomes using midazolam as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
14. | ALA5118023 | A | Inhibition of CYP1A2 in rat liver microsomes using phenacetin as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
15. | ALA5118024 | A | Inhibition of CYP2D1 in rat liver microsomes using dextromethorphan as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
16. | ALA5118025 | A | Inhibition of CYP2E1 in rat liver microsomes using chlorzoxazone as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
17. | ALA5118026 | A | Inhibition of CYP2C6 in rat liver microsomes using diclofenac as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature | |
18. | ALA5118027 | F | Antitumor activity against mouse 4T1 cells implanted in mouse assessed as tumor growth inhibition at 5 mg/kg administered for 15 days relative to control | Mus musculus | 1 | ALA5113488 | organism-based format | Scientific Literature | |
19. | ALA5118028 | F | Antitumor activity against mouse 4T1 cells implanted in mouse assessed as tumor growth inhibition at 10 mg/kg administered for 15 days relative to control | Mus musculus | 2 | ALA5113488 | organism-based format | Scientific Literature | |
20. | ALA5118029 | T | Toxicity in mouse implanted with mouse 4T1 cells assessed as body weight loss at 5 to 10 mg/kg administered for 15 days | Mus musculus | 1 | ALA5113488 | organism-based format | Scientific Literature |